Bio-Degradable Glass for Neural Probe Application

Abstract:

This work presents a bio-degradable glass probes and its biocompatibility assessment for neural applications. The probes can be implanted into different sites of the human brain for recording and stimulating purposes. Current existing neural probe address the probe stiffness requirement for the penetration of brain tissue. However, this requirement normally resulted in the rigidity of the probe which is non-compatible with the brain tissue movement for long term implantation. The brain neuron cells will be damaged by too rigid probe substrate. In order to address this issue, bio-degradable glass probes having sufficient stiffness for a smooth brain insertion as well as ability to degrade after implantation; leaving behind the flexible circuitry substrate was being explored. The biodegradability of the proposed probe was evaluated.

• Periodical: Advanced Materials Research (Volume 740)
• Pages: 555-559
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.740.555
• Online since: August 2013
• Authors: Rui Qi Lim, Kwan Ling Tan, Wei Guo Chen, Mink Yu Je, Tack Boon Yee, Ming Yuan Cheng
• Keywords: Biocompatibility, Bio-Degradable Glass, Neural Probe

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