Study about the Relationship between TNF-Α-308G/A and Essential Hypertension in Specific Population-Taking Chinese Minority Zhuang in Guangxi as an Example

Xing Shou Pan; Ke Xing Lu; Tian Zi Li

doi:10.4028/www.scientific.net/AMR.749.149

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 749Study about the Relationship between TNF-Α-308G/A...

Study about the Relationship between TNF-Α-308G/A and Essential Hypertension in Specific Population-Taking Chinese Minority Zhuang in Guangxi as an Example

Abstract:

objective: study the association between TNF gene and essential hypertension (EH) in Chinese minority Zhuang population. Method: select 170 normal as control group and 246 patients with EH as an object of study, use polymerase chain reaction - restriction fragment length polymorphism method to analyze polymorphic loci in the promoter region of TNF-α gene-308G / A allele, and genotype frequency distribution characteristics were analyzed, and the relationship between genetic susceptibility polymorphisms and EH was given.

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Periodical:

Advanced Materials Research (Volume 749)

Pages:

149-153

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.749.149

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Online since:

August 2013

Authors:

Xing Shou Pan, Ke Xing Lu, Tian Zi Li

Keywords:

Essential Hypertension, Gene Polymorphism, Tumor Necrosis Factor

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