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Enrichment of Peptide with Graphene for MALDI-TOF MS Analysis

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Abstract:

In this paper, graphene was used as the adsorbent for peptide enrichment, and followed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) analysis. To study the adsorptive property of graphene, peptide angiotensin II was chosen as the model target. The enrichment material was analyzed by MALDI-TOF MS directly without desorption step. As a result, graphene showed good adsorptive capacity for peptide. After enrichment, the peak intensity and the signal-to-noise ratio were obviously increased.

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Periodical:

Advanced Materials Research (Volumes 781-784)

Pages:

111-114

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.781-784.111

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Online since:

September 2013

Authors:

Neng Sheng Ye*, Ya Li Xie, Chang Liu, Jian Li

Keywords:

Enrichment, Graphene (GR), MALDI-TOF MS Analysis, Peptide

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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