Preparation and Biological Activity of Chitosan Fibers Reinforced PLLA/HA-CaSiO3 Composites

Jing Wang; Hong Bo Li; Jing Gao; Xiang Cai Meng

doi:10.4028/www.scientific.net/AMR.79-82.2055

Paper Titles

Functional Silica Aerogels with High Specific Surface Area: Influence of Preparation Conditions on Structure Properties
p.2039

Synthesis and Characterization of Water-Soluble Cu²⁺-Doped ZnSe Quantum Dots
p.2043

Fire-Damage or Freeze-Thaw of Strengthening Concrete Using Ultra High Performance Concrete
p.2047

Pyrolysis Kinetic of Basic Zinc Carbonate from Spent Catalyst and Preparation of Active ZnO by Microwave Heating
p.2051

Preparation and Biological Activity of Chitosan Fibers Reinforced PLLA/HA-CaSiO₃ Composites
p.2055

Synthesis and the Characterizations of Structure and Function of Gallic Acid Microcrystalline Cellulose Ester
p.2059

Electrical Response and Mechanical Behavior of Plasticized PVC Actuators
p.2063

Effect of Disbond Propagation on the Reflected Spectra of CFBG Sensors Embedded within the Bondline of Composite Bonded Joints
p.2067

Influence of Zinc-Zirconium Substitution on Magnetic Properties of Ba(ZnZr)_xFe_12-2xO₁₉ Hexaferrite Prepared by the Molten Salt Method
p.2071

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 79-82Preparation and Biological Activity of Chitosan...

Preparation and Biological Activity of Chitosan Fibers Reinforced PLLA/HA-CaSiO₃ Composites

Abstract:

Chitosan fibers(CSf) andCaSiO3 were incorporated into a poly (L-lactic acid)/hydroxyapatite (PLLA/HA) matrix as reinforcements to prepare scaffold composites with adequate strength and high porosity for bone tissue engineering combined with emulsion freeze drying technique. The structural morphology of the composites was observed by scanning electron microscope (SEM). The porosity was tested by liquid substitute method. The mechanical property was measured. The effects of addition of CSf and CaSiO3 on composites were also discussed. Simulated body fluid (SBF) experiments were conducted to assess the bioactivity of the composites. The chemical components of resultants on surfaces after the immersion in SBF were analyzed by fourier transform infrared spectroscopy (FTIR). The results show that the composites with high connectivity have pore sizes of 100~250μm, a porosity of 60%~80%, compressive strength of 3.5~8.0MPa. In the SBF tests, Chitosan fiber reinforced PLLA/HA-CaSiO3 composite degraded stably, meanwhile, the formation of a layer of bone-like apatite on the surfaces of the samples indicated a good bioactivity. Studies suggest the feasibility of using CSf reinforced PLLA /HA-CaSiO3 composite for bone tissue engineering.

You might also be interested in these eBooks

Multi-Functional Materials and Structures II

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 79-82)

Pages:

2055-2058

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.79-82.2055

Citation:

Cite this paper

Online since:

August 2009

Authors:

Jing Wang, Hong Bo Li, Jing Gao, Xiang Cai Meng

Keywords:

Biological Activity, Chitosan Fibers, PLLA/HA-CaSiO₃Composite, Structural Morphology

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] X H. Wang, D P LI, W J Wang: Biomaterials Vol. 24(2003), p.3213.

Google Scholar

[2] J B. LIU and J T. CHEN: Modern Rehabilitation Vol. 5(4)( 2001), p.68.

Google Scholar

[3] Y Q . DONG, C CAO, Y H. DONG and Y Y. LIU: Academic Journal of Shanghai Second Medical University Vol. 25(9) (2005), p.906.

Google Scholar

[4] Chuen-How Ng, San Hein, Suwalee Chandrkrachang and Willem F. Stevens: Journal of Biomedical Materials Research Part B: Applied Biomaterials Vol. 76B(1) (2005), pp.155-160.

DOI: 10.1002/jbm.b.30353

Google Scholar

[5] Klokkevokl P R, Vandemsrk L , Kennev EB, et al : J Periodoto Vol. 67(11)(1996).

Google Scholar