Surface Characterization of Poly(DL-Lactide-co-Glycolide) (PLGA) Membranes Fabricated by the Various Methods for Biomedical Applications

Fu Juan Liu

doi:10.4028/www.scientific.net/AMR.796.333

Paper Titles

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Preparation of PVDF Nanofibrous Membrane and its Waterproof and Breathable Property
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Surface Characterization of Poly(DL-Lactide-co-Glycolide) (PLGA) Membranes Fabricated by the Various Methods for Biomedical Applications
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The Preparation of Transfer Paper for Novel Silk Transfer Printing
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Analysis on the Differences of Color Fastness Standard of Textiles at Home and Abroad
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Research of Salt-Free Dyeing of Reactive Dyes on Chitosan Quaternary Ammonium Salt Treated Bombyx mori Silk Fabric
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Fabrication of ZnO Nanoparticles by Hyperbranched Polymer and their Application on the Functional Finishing of Cotton Fabric
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 796Surface Characterization of...

Surface Characterization of Poly(DL-Lactide-co-Glycolide) (PLGA) Membranes Fabricated by the Various Methods for Biomedical Applications

Abstract:

A systematic study on molecular structure of Poly (DL-lactide-co-glycolide) (PLGA) films by the methods of being chemically immobilized onto self-assembled monolayers (SAMs) and spin coating using Fourier transform infrared spectroscopy (FTIR), sum frequency generation (SFG) vibrational spectroscopy is reported. Especially, a surface sensitive second order nonlinear optical technique, SFG vibrational spectroscopy, was applied to study molecular structure on PLGA films. It is shown that the more chemical groups of PLGA thin films with being chemically immobilized have orientation than that of PLGA films made by spin coating on the basis of SFG vibrational spectroscopy data. The characterization of the other analytical techniques indicates similar results. This work will be an important step for future biomaterials design and understanding biosensors, biocompatibility and biomacromolecule (e.g. proteins and peptides) activity.