Fabrication of Strong Photoluminescent Carbon Nanodots and its Preliminary Application in Cell Imaging

Abstract:

Water-soluble fluorescent carbon nanodots (C-dots) with strong photoluminescence were synthesized on a large scale by a facile, one-step and mild pyrolytic route using ammonium citrate as carbon source. The as-prepared C-dots exhibited low cytotoxicity, excellent biocompatibility and preeminent multicolor photoluminescent properties. Furthermore, the cellular internalization of the obtained C-dots was evaluated and the results reconfirmed the C-dots potentials for bioimaging.

• Periodical: Advanced Materials Research (Volume 800)
• Pages: 312-316
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.800.312
• Online since: September 2013
• Authors: Fan Li, Chang Jun Liu, Feng Tian, Jian Yang, Zhi Hong Li
• Keywords: Carbon Nanodots, Cell Imaging, Photoluminescence (PL)

References

[1] X. Y. Xu, R. Ray, Y. L. Gu, H. J. Ploehn, L. Gearheart, K. Raker, W. A. Scrivens, Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments, J. Am. Chem. Soc., 126 (2004) 12736-12737.

DOI: 10.1021/ja040082h

[2] S. T. Yang, L. Cao, P. G. Luo, F. Lu, X. Wang, H. Wang, M. J. Meziani, Y. Liu, G. Qi and Y. P. Sun, Carbon Dots for Optical Imaging in vivo, J. Am. Chem. Soc., 131 (2009) 11308-11309.

DOI: 10.1021/ja904843x

[3] F. Wang, Y. H. Chen, C. Y. Liu and D. G. Ma, White light-emitting devices based on carbon dots' electroluminescence, Chem. Commun., 47 (2011) 3502-3504.

DOI: 10.1039/c0cc05391k

[4] Baker SN and Baker GA, Luminescent Carbon Nanodots: Emergent Nanolights, Angew. Chem. Int. Ed., 49 (2010) 6726-6744.

DOI: 10.1002/anie.200906623

[5] L. Cao, X. Wang, M. J. Meziani, F. S. Lu, H. F. Wang, P. J. G. Luo, Y. Lin, B. A. Harruff, L. M. Veca, D. Murray, S. Y. Xie and Y. P. Sun, Carbon dots for multiphoton bioimaging, J. Am. Chem. Soc., 129 (2007) 11318-11319.

DOI: 10.1021/ja073527l

[6] Q. L. Zhao, Z. L. Zhang, B. H. Huang, J. Peng, M. Zhang and D. W. Pang, Facile preparation of low cytotoxicity fluorescent carbon nanocrystals by electrooxidation of graphite, Chem. Commun., (2008) 5116-5118.

DOI: 10.1039/b812420e

[7] J. G. Zhou, C. Booker, R. Y. Li, X. T. Zhou, T. K. Sham, X. L. Sun and Z. F. Ding, An electrochemical avenue to blue luminescent nanocrystals from multiwalled carbon nanotubes (MWCNTs), J. Am. Chem. Soc., 129 (2007) 744-745.

DOI: 10.1021/ja0669070

[8] H. P. Liu, T. Ye and C. D. Mao, Fluorescent Carbon Nanopar- ticles Derived from Candle Soot, Angew. Chem. Int. Ed., 46 (2007) 6473-6475.

DOI: 10.1002/anie.200701271

[9] A. B. Bourlinos, A. Stassinopoulos, D. Anglos, R. Zboril, M. Karakassides, E. P. Giannelis, Surface functionalized carbogenic quantum dots, Small, 4 (2008) 455-458.

DOI: 10.1002/smll.200700578

[10] C. J. Liu, P. Zhang, F. Tian, W. C. Li, F. Li and W. G. Liu, One-step synthesis of surface passivated carbon nanodots by microwave assisted pyrolysis for enhanced multicolor photoluminescence and bioimaging, J. Mater. Chem., 21 (2011).

DOI: 10.1039/c1jm12744f

[11] F. Wang, S. P. Pang, L. Wang, Q. Li, M. Kreiter and C. Y. Liu, One-Step Synthesis of Highly Luminescent Carbon Dots in Noncoordinating Solvents, Chem. Mater., 22 (2010) 4528-4530.

DOI: 10.1021/cm101350u

[12] H. T. Li, X. D. He, Y. Liu, H. Huang, S. Y. Lian, S. T. Lee, Z. H. Kang, One-step ultrasonic synthesis of water-soluble carbon nanoparticles with excellent photoluminescent properties, Carbon. 49 (2011) 605-609.

DOI: 10.1016/j.carbon.2010.10.004

[13] A. Rahy, C. Zhou, J. Zheng, S. Y. Park, M. J. Kim, I. Jang, S. J. Cho, D. J. Yang, Photoluminescent Carbon Nanoparticles Produced by Confined Combustion of Aromatic Compounds, Carbon, 50 (2012) 1298-1302.

DOI: 10.1016/j.carbon.2011.10.052