Synthesis of Co/TiO₂ Nanocomposite and its Use in Construction of a Sensitive and Selective Sensor for Determination of Ciprofloxacin

Abstract:

The Co/TiO₂ nanocomposite was synthesized by a modified sol-gel method. The surface structure and composition of nanoparticles were characterized by scanning electron microscopy (SEM), X-ray powder diffraction analysis (XRD), Fourier transform infrared (FTIR) spectrometry, thermal gravimetric analysis (TGA) and N₂ physisorption. A carbon paste electrode (CPE) modified with Co/TiO₂ nanocomposite was prepared and used for low level determination of antibiotic ciprofloxacin (CF) using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Under optimized conditions, the modified electrode exhibited a linear response over the concentration range of 0.1 to 70 μM CF, with a detection limit of 0.03 μM. The proposed sensor was applied to the CF determination in serum and urine samples.

• Periodical: Advanced Materials Research (Volume 829)
• Pages: 563-567
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.829.563
• Online since: November 2013
• Authors: Mojtaba Shamsipur*, Mohammad Bagher Gholivand, Sara Dehdashtian, Mostafa Feyzi, Fataneh Jafari
• Keywords: Ciprofloxacin, Cyclic Voltammetry (CV), Differential Pulse Voltammetry, Modified Carbon Paste Electrode, Nanocomposite, Scanning Electron Microscopy (SEM)

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