A Novel Synthesis of Glycosylated AZT-5'-Phosphoramidates

Abstract:

A novel and efficient method for the synthesis of O-AZT-5-O-glycosyl-1-phosphoramidate diesters via H-phosphonate intermediates has been developed.

• Periodical: Advanced Materials Research (Volume 848)
• Pages: 211-214
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.848.211
• Online since: November 2013
• Authors: Cha Ma, Guo Dong Liu, Xing Jian Li, Shan Shan Gong, Qi Sun*
• Keywords: Antiviral Nucleoside, AZT, H-Phosphonate Diester, Phosphoramidate Diester, Prodrug

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