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A Novel Synthesis of 3-Bromo-1,2-Propanediol from 3-Oxetanol

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Abstract:

Treatment of 3-oxetanol with carbon tetrabromide (CBr4) and triphenylphosphine (PPh3) under mild condition provides an efficient route for synthesis of 3-bromo-1,2-propanediol. The experimental results showed that an unexpected ring-opening reaction was selectively achieved under the routine bromination reaction condition.

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Advanced Research on Energy, Chemistry and Materials Application View Preview

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Periodical:

Advanced Materials Research (Volume 848)

Pages:

219-222

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.848.219

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Online since:

November 2013

Authors:

Jian Sun, Shan Shan Gong, Qi Sun*

Keywords:

3-Bromo-1,2-Propanediol, 3-Oxetanol, Carbon Tetrabromide, Ring-Opening Reaction, Triphenylphosphine

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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References

[1] V. B. Birman, S. J. Danishefsky, J. Am. Chem. Soc., Vol. 124 (2002), p. (2080).

Google Scholar

[2] C. G. Derick, D. W. Bissell, J. Am. Chem. Soc, Vol. 38 (1916), p.2478.

Google Scholar

[3] J. Burkhard, E. M. Carreira, Org. Lett., Vol. 10 (2008), p.3525.

Google Scholar

[4] M. Micuno, M. Kanai, A. Iida, K. Tomioka, Tetrahedron, Vol. 53 (1997), p.10699.

Google Scholar

[5] S. A. Carr, W. P. Weber, J. Org. Chem., Vol. 50 (1985), p.2782.

Google Scholar

[6] F. Bertolini, S. Crotti, V. D. Bussolo, F. Macchia, M. Pineschi, J. Org, Chem., Vol. 73 (2008), p.8998.

Google Scholar

[7] I. Downie, J. Holmes, J. Lee, Chemistry and Industry, Vol. 22 (1984), p.900.

Google Scholar

[8] H. J. Liu, T. Dieck-Abularach, Heterocycles, Vol. 25 (1987), p.245.

Google Scholar

[9] K. Yamakawa, T. Tominage, K. Nishiaini, Tetrahedron Lett., (1975), p.4137.

Google Scholar

[10] S. Winstein, L. Goodman, J. Am. Chem. Soc., Vol. 76 (1954), p.4368.

Google Scholar

[11] K. Baum, P. T. Berkowitz, V. Grakauskas, T. G. Archibald, J. Org. Chem., Vol. 76 (1954), p.4368.

Google Scholar

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