Study on the Making of Amphiphilic Triblock Copolymer as Blood Substitutes

Yan Chun Ma; Li Ying Cai; Wen Bo Cui; Ying Gao; Yun Hui Li

doi:10.4028/www.scientific.net/AMR.881-883.450

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 881-883Study on the Making of Amphiphilic Triblock...

Study on the Making of Amphiphilic Triblock Copolymer as Blood Substitutes

Abstract:

Abstract:The blood substitutes refer to the substitutes of red blood cell with the ability to carry oxygen. This paper adopts open-loop coordination polymerization and gets amphiphilic triblock copolymer of mPEG-PAGE-PDLLA with the hydrophilic end-mPEG segment, and hydrophobic end-PLA segment. And it can be automatically assembled into vesicles in the water. The hemoglobin nanoparticles can be obtained by combining with Vesicle-coated hemoglobin, which are independently blended with oxygen and biodegradable. Meanwhile the paper makes an analysis of various physical and chemical properties to hemoglobin nanoparticles.

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Periodical:

Advanced Materials Research (Volumes 881-883)

Pages:

450-456

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.881-883.450

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Online since:

January 2014

Authors:

Yan Chun Ma, Li Ying Cai, Wen Bo Cui, Ying Gao, Yun Hui Li

Keywords:

Blood Substitutes, Copolymer, Hemoglobin, Vesicles

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