Fabrication and Characterization of P34HB Scaffolds with Oriented Microtubules

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Abstract:

Sponge-like scaffold with a specific three-dimensional structure resembling the actual extracellular matrix of a particular tissue show significant potential for the regeneration and repair of damaged anisotropic tissues. In this research, an oriented microtubular P34HB scaffold was prepared successfully. The mechanical property showed that anisotropy of modulus is much greater than a typical non-oriented scaffold. Altering the P34HB concentration allowed P34HB scaffolds to be produced with complex pore orientations, and anisotropy in pore size and alignment.

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318-321

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February 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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