The Drug Loading Thermodynamics Mechanism of Eight Cationic Drugs’ Adsorption onto Ion Exchange Fiber

Hui Min Yao; Jun Yi Zhu; Guang Qing Xia

doi:10.4028/www.scientific.net/AMR.901.41

Paper Titles

Phase-Shifted Bragg Gratings Based on Hybrid Plasmonics Structure
p.21

Surface Enhanced Raman Scattering Based on Dielectric-Loaded Surface Plasmon Polariton Waveguides
p.25

A Novel System for Fine Particle Concentration Measurement
p.29

Polymerization of Acrylamide Photo Initiated by Ferroferric Oxide Nanoparticles
p.35

The Drug Loading Thermodynamics Mechanism of Eight Cationic Drugs’ Adsorption onto Ion Exchange Fiber
p.41

Removal of Heavy Metal Ions with Hacac-Silica
p.45

Investigation of Room Temperature Photoluminescence of ZnO Films Induced by Different Laser Fluence Irradiation
p.53

The Desalination Device Using the Rising Liquid Film on the Microscale Fluted Surface of Horizontal Tubes
p.59

Long-Range Air-Hole Assisted Subwavelength Waveguides: Towards Large-Scale Photonic Integration
p.65

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 901The Drug Loading Thermodynamics Mechanism of Eight...

The Drug Loading Thermodynamics Mechanism of Eight Cationic Drugs’ Adsorption onto Ion Exchange Fiber

Abstract:

The adsorption of eight drugs (Log P range from-2.64~8.98) was investigated by performing batch adsorption experiments. Experiments were carried out as function of contact time, initial concentration and temperature (25-60°C). The equilibrium adsorption data of drugs on ion-exchange fiber were analyzed by Langmuir and Freundlich models. The results indicate that the Langmuir model provides the best correlation of the experimental data. The results indicate that ion-exchange fiber is suitable as drug carriers for loading drugs.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 901)

Pages:

41-44

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.901.41

Citation:

Cite this paper

Online since:

February 2014

Authors:

Hui Min Yao, Jun Yi Zhu*, Guang Qing Xia

Keywords:

Adsorption, Cationic Drug, Ion-Exchange Fiber, Thermodynamic

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] Alkan M., Dogan M., 2003. Adsorption kinetics of Victoria blue onto perlite, Fresen. Environ. Bull. 12 : 418–425.

Google Scholar

[2] Anand V, Kandarapu R, Garg S., 2001. Ionexchange resins: Carrying drug delivery forward. DDT 6: 905–914.

DOI: 10.1016/s1359-6446(01)01922-5

Google Scholar

[3] Azizian S., 2004. Kinetic models of sorption: a theoretical analysis, J. Colloid Interf. Sci. 276: 47–52.

Google Scholar

[4] Chen L, Yang G, Zhang J., 1996. A study on the exchange kinetics of ion-exchange fiber. React Funct Polym 29: 139–144.

Google Scholar

[5] Conaghey OM, Corish J, Corrigan OI. 1998. Iontophoretically assisted in vitro membrane transport of nicotine from a hydrogel containing ion exchange resins. Int J Pharm 170: 225–237.

DOI: 10.1016/s0378-5173(98)00145-8

Google Scholar

[6] Freundlich H.M.F., 1906. Uber die adsorption in losungen, J. Phys. Chem. 57: 385–470.

Google Scholar

[7] Hameed B., Ahmad A., Aziz N. 2007. Isotherms, kinetics and thermodynamics of acid dye adsorption on activated palm ash. Chem. Eng. Journal 133: 195–203.

DOI: 10.1016/j.cej.2007.01.032

Google Scholar

[8] Hirvonen J. 2002. Improved stability and release control of levodopa and metaraminol using ion-exchange fibers and transdermal iontophoresis. Eur J Pharm Sci 6: 273–280.

DOI: 10.1016/s0928-0987(02)00113-6

Google Scholar

[9] Irwin WJ, MacHale R, Watts PJ. 1990. Drug delivery by ion-exchange. Part VII: Release of acidic drugs from anionic exchange resinate complexes. Drug Dev Ind Pharm 16: 883–898.

DOI: 10.3109/03639049009114916

Google Scholar

[10] Illum L. 1999. Nasal drug delivery composition containing nicotine. U.S. Patent 5, 935, 604, August 10.

Google Scholar

[11] Jani R, Gan O, Ali Y, Rodstrom R, Hancock S. 1994. Ion exchange resins for ophthalmic delivery. J Ocul Pharmacol 10: 57–67.

DOI: 10.1089/jop.1994.10.57

Google Scholar

[12] Langmuir I., 1918. Adsorption of gases on plain surfaces of glass mica platinum,J. Am. Chem. Soc. 40: 136–403.

Google Scholar