Nanoscale DNA Sensing-Potential and Prospects

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Nanomaterials have attractive physico-chemical properties to create building block for special reorganization of DNA molecule. Nanomaterial based DNA sensors can be constructed with atomic precision, enhancing sensitivity and performance. Gold nanoparticles have excellent properties for tailoring size and shape to architect nanoscale structure, enhancing sensing and detection capacity by several magnitudes. Carbon nanotubes can immobilize probe DNA molecule and amplify signal transduction. Silica-nanoparticles based DNA detection inward significant attention because of their small size and ultra-scale sensitivity. Quantum dots have size-dependent adaptable photoluminescence with capability to perform multiplex detection. This paper has reviewed potential nanomaterials for DNA sensing application.

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486-489

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April 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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