Flow Field Analysis and Response Surface Research on the Rotor in Dry Powder Inhaler

Zhi Chen Cao; Hao Ying Li; Shi Hong Shi; En Long Zhou

doi:10.4028/www.scientific.net/AMR.983.242

Paper Titles

UV-Radiation Curing Process of Cationic Epoxy Adhesive Materials
p.222

ABAQUS Based on Machining Simulation during Metal Milling
p.226

Design Study of Small Gas Cooled Fast Nuclear Power Plant for Synergetic Energy System with Renewable Energy by Employing Pump Storage
p.233

Electrochemical Performance of LiFePO₄/C Prepared from Different Carbon Source
p.238

Flow Field Analysis and Response Surface Research on the Rotor in Dry Powder Inhaler
p.242

Gas Permeation Properties and Characterization of Polymer Based Carbon Membrane
p.246

Measurement Principle of Glass Thermal Expansion Coefficient and Technology Application of DIL402PC Dilatometer
p.251

Methodology of Taguchi Optimization for Organic Rice Bran to Maximum Antioxidant Activity
p.257

Resolving National Energy Crisis through Energy Efficient Appliances: Use of Ground Water Heat Pump for Air Conditioning Systems
p.261

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 983Flow Field Analysis and Response Surface Research...

Flow Field Analysis and Response Surface Research on the Rotor in Dry Powder Inhaler

Abstract:

In order to find out the correspond relationship of the outlet velocity and rotor speed in dry powder inhaler, the intermediate parameter was inserted in Workbench response surface based on CFD. The simulation of the suction drive rotor rotation mechanism was based on MRF model in FLUENT. It can be easily obtained the rotor’s performance curve under different aerodynamic conditions and found out the optimized flow rate is 66.127L/min. This method verifies the clinical phenomena and could guide the clinical research and machinery optimization.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 983)

Pages:

242-245

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.983.242

Citation:

Cite this paper

Online since:

June 2014

Authors:

Zhi Chen Cao, Hao Ying Li*, Shi Hong Shi, En Long Zhou

Keywords:

CFD, Dry Powder Inhaler, Numerical Simulation, Response Surface, Rotor

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] Islam N, Gladki E. Dry powder inhalers (DPIs)—a review of device reliability and innovation [J]. International Journal of Pharmaceutics, 2008, 360(1): 1-11.

DOI: 10.1016/j.ijpharm.2008.04.044

Google Scholar

[2] Bernstein J A, Amin H, Smith S J. Therapeutic uses of lung aerosol [J]. Lung Biology in Health and Disease, 2007, 221: 219.

Google Scholar

[3] Chen X M. New progress of pulmonary delivery [J]. Chinese Journal of Modern Drug Application, 2010, 4(001): 224-226.

Google Scholar

[4] Zhang W, Jia Y, Zhang W M, etc. Comparative simulation of engine cooling fan of mining dump truck based on CFD [J]. Coal Mine Machinery, 2012, 12: 026.

Google Scholar

[5] Shao S Q, Lu D W, Jeon W H. Numerical analysis on the flow noise in the indoor unit and cross flow fan of air-conditioners [J]. Journal of Refrigeration, 2012, 33(3): 9-13.

Google Scholar

[6] Chen X J, Li Y, Xia L F, etc. Simulation analysis on internal flow field characteristics of engine cooling fan for construction machinery [J]. Construction Machinery and Equipment, 2011, 42(11): 21-24.

Google Scholar