Rice Husk Ash Filled with Hydroxyapatite Based Composite for Biomedical Application

Abstract:

Despite several advantages of hydroxyapatite, the main shortcoming is its low mechanical properties. The aim of the research study is the production and characterization of Rice Husk Ash reinforced hydroxyapatite ceramic composite for bone repair. The effect of Rice Husk Ash content and sintering temperature on the wear rate, physical and mechanical properties of the fabricated composite was investigated. The porosities obtained for the samples range from 39±0.1 to 56.53±0.14%. The porosity obtained in this study falls within the range of 40 and 90% which makes it suitable for osteo-integration. The trend from the mechanical properties shows that the addition of the rice husk ash significantly improves the measurement since it serves as a barrier to the propagation of cracks and consequently serves as an additional toughening mechanism. The wear rates obtained for the samples are 0.036, 0006, 0.0016, 0.009 for 0, 0.5, 1, and 1.5 wt.%RHA respectively. This shows that the wear rate of the samples reduces drastically with the addition of the rice husk.

• Periodical: Advances in Science and Technology (Volume 154)
• Pages: 121-130
• DOI: https://doi.org/10.4028/p-9myhcF
• Online since: July 2024
• Authors: Muhammad A. Adamu*, Emmanuel O. Ameh, Salami A. Kazeem, Mohammed Abdullahi, Uman Hassan
• Keywords: Hydroxyapatite, Mechanical Properties, Porosities, Rice Husk Ash, Wear Rate

References

[1] A. J. W. Johnson, B. A. Herschler, A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair. Acta biomaterialia, 7(1) (2011) 16-30.

DOI: 10.1016/j.actbio.2010.07.012

[2] A. Szcześ, L. Hołysz, E. Chibowski, Synthesis of hydroxyapatite for biomedical applications. Advances in colloid and interface science, 249 (2017) 321-330.

DOI: 10.1016/j.cis.2017.04.007

[3] N. I. Agbeboh, I. O. Oladele, O. O. Daramola, A. D. Akinwekomi, M. O. Tanimola, O. Olasukanmi, Comparing the effects of two wet precipitation methods on the yield of chicken eggshell-derived hydroxyapatite. Futa J. Eng. Eng. Technol, 16 (2022) 95-104.

DOI: 10.51459/futajeet.2022.16.1.350

[4] T. Billiet, M. Vandenhaute, J. Schelfhout, S. Van Vlierberghe, P. Dubruel, A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering. Biomaterials, 33(26) (2012) 6020-6041.

DOI: 10.1016/j.biomaterials.2012.04.050

[5] V. Sansone, D. Pagani, M. Melato, The effects on bone cells of metal ions released from orthopaedic implants. A review. Clinical Cases in Mineral and Bone Metabolism, 10(1) (2013) 34.

DOI: 10.11138/ccmbm/2013.10.1.034

[6] B. D. Ulery, L. S. Nair, C. T. Laurencin, Biomedical applications of biodegradable polymers. Journal of polymer science Part B: polymer physics, 49(12) (2011) 832-864.

DOI: 10.1002/polb.22259

[7] G. M. Raghavendra, K. Varaprasad, T. Jayaramudu, Biomaterials: design, development and biomedical applications. In Nanotechnology applications for tissue engineering William Andrew Publishing. 2015.

DOI: 10.1016/b978-0-323-32889-0.00002-9

[8] K. Wang, C. Zhou, Y. Hong, X. Zhang, A review of protein adsorption on bioceramics. Interface focus, 2(3) (2012) 259-277.

DOI: 10.1098/rsfs.2012.0012

[9] J. S. Temenoff, A. G. MikosBiomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River, NJ, USA: Pearson/Prentice Hall, 2008.

[10] D. O. Obada, S. A. Osseni, H. Sina, A. N. Oyedeji, K. A. Salami, E. Okafor,... E. T. Dauda, Hydroxyapatite materials-synthesis routes, mechanical behavior, theoretical insights, and artificial intelligence models: a review. Journal of the Australian Ceramic Society, 59(3) (2023) 565-596.

DOI: 10.1007/s41779-023-00854-2

[11] K. J. Burg, S. Porter, J. F. Kellam, Biomaterial developments for bone tissue engineering. Biomaterials, 21(23) (2000) 2347-2359.

DOI: 10.1016/s0142-9612(00)00102-2

[12] I. R. Oliveira, T. L. Andrade, K. C. M. L. Araujo, A. P. Luz, V. C. Pandolfelli, Hydroxyapatite synthesis and the benefits of its blend with calcium aluminate cement. Ceramics International, 42(2) (2016) 2542-2549.

DOI: 10.1016/j.ceramint.2015.10.056

[13] R. Z. LeGeros, Calcium phosphate-based osteoinductive materials. Chemical reviews, 108(11) (2008) 4742-4753.

DOI: 10.1021/cr800427g

[14] D.O. Obada, S.A. Osseni, H. Sina, A.N. Oyedeji, K.A. Salami, E. Okafor, E.T. Dauda, Hydroxyapatite materials-synthesis routes, mechanical behavior, theoretical insights, and artificial intelligence models: a review. Journal of the Australian Ceramic Society, 1-32. (2023)

DOI: 10.1007/s41779-023-00854-2

[15] M. A. Adamu, M. Sumaila, M. Dauda, & T. Ause, Production and optimization of novel rice husk ash reinforced polycaprolactone/hydroxyapatite composite for bone regeneration using grey relational analysis. Scientific African, 19 (2023) e01563.

DOI: 10.1016/j.sciaf.2023.e01563

[16] X. Zhao, L. Zhang, X. Wang, J. Yang, F. He, Y. Wang, Preparation and mechanical properties of controllable orthogonal arrangement of carbon fiber reinforced hydroxyapatite composites. Ceramics International, 44(7) (2018) 8322-8333.

DOI: 10.1016/j.ceramint.2018.02.020

[17] D. Arcos, M. Vallet-Regí, Sol–gel silica-based biomaterials and bone tissue regeneration. Acta biomaterialia, 6(8), (2010) 2874-2888.

DOI: 10.1016/j.actbio.2010.02.012

[18] E. S. Akpan, M. Dauda, L. S. Kuburi, D. O. Obada, D. Dodoo-Arhin, A comparative study of the mechanical integrity of natural hydroxyapatite scaffolds prepared from two biogenic sources using a low compaction pressure method. Results in Physics, 17, (2020) 103051.

DOI: 10.1016/j.rinp.2020.103051

[19] A. Kusakabe, K. Hirota, T. Mizutani, Crystallisation of hydroxyapatite in phosphorylated poly(vinyl alcohol) as a synthetic route to tough mechanical hybridmaterials. Mater. Sci. Eng. C 70, (2017) 487–493.

DOI: 10.1016/j.msec.2016.09.006

[20] D. O. Obada, E. T. Dauda, J. K. Abifarin, N. D. Bansod, D. Dodoo-Arhin, Mechanical measurements of pure and kaolin reinforced hydroxyapatite-derived scaffolds: A comparative study. Materials Today: Proceedings, 38, (2021) 2295-2300.

DOI: 10.1016/j.matpr.2020.06.412

[21] T. Wu, J. Su, Y. Li, H. Zhao, Y. Zhang, M. Zhang, B. Wu, Wear resistance mechanism of alumina ceramics containing Gd2O3. Materials, 11(10), (2018) 2054.

DOI: 10.3390/ma11102054

[22] S. Kannan, S. I. Vieira, S. M. Olhero, S. Pina, O. D. C. Silva, J. M. F. Ferreira, Synthesis, mechanical and biological characterization of ionic doped carbonated hydroxyapatite/β-tricalcium phosphate mixtures. Acta Biomaterialia, 7(4), (2011)1835-1843.

DOI: 10.1016/j.actbio.2010.12.009

[23] G. Anbalagan, A. R. Prabakaran, S. Gunasekaran, Spectroscopic characterization of indian standard sand. Journal of Applied Spectroscopy, 77(1), (2010) 86–94.

DOI: 10.1007/s10812-010-9297-5

[24] V. Karageorgiou, D. Kaplan, Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26 (27), (2005) 5474–5491.

DOI: 10.1016/j.biomaterials.2005.02.002

[25] J. Ren, K. Kyohan, K Seock Sam, Jingri Ren, Kyohan Kim, Seock Sam Kim. Fracture and tribological evaluation of dental composite resins containing pre-polymerized particle fillers. J Mater Sci Technol,19(3), (2003) 249e52.