A Theoretical Model to Fracture in Cell Membrane

Abstract:

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A new stress function modelling the fails in biological tissue is here proposed. Under the assumption that the cell membrane may be modelled as neo-Hookean materials, we develop the problem in the framework of non-linear elasticity. We attempt to model the ice nucleation phenomenon when freezing and thawing occurs in cellular cryo-preservation. The ice seed generated surface can be either soft or wrinkled and, when the latter emerges a punch contact against the cell membrane takes place. Restricting our attention on opportune mono-dimensional sub-set, we extend the multiple critical points theorem at our model. We find a particular solution in agreement to the classical fracture models besides a response function in accordance to the stress and strain field distribution in biological materials.

Info:

Pages:

67-71

DOI:

10.4028/www.scientific.net/JBBTE.11.67

Citation:

M. Buonsanti and A. Pontari, "A Theoretical Model to Fracture in Cell Membrane", Journal of Biomimetics, Biomaterials and Tissue Engineering, Vol. 11, pp. 67-71, 2011

Online since:

September 2011

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$35.00

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