Preparation of Hydroxyapatite-Fibroin Nanocomposites

Article Preview

Abstract:

Nanocomposites of hydroxyapatite-fibroin (HA-FB) were prepared using the biomimetic process. The Nanocomposites were detected with X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). The FTIR results showed that chemical bond forms between HA nanocrystals and fibroin protein. The secondary structure of fibroin can be affected by the mineralization process. TGA results indicated the content of mineralized fibroin in the nanocomposites can be freely adjusted by changing the initial concentration of fibroin solution. TEM image showed that the diameter of the single mineralized nanofibrils is about 2-3 nm and the nanofibrils can aggregate into bundles with the size of 6-8 nm in width and 30-60 nm in length.

You might also be interested in these eBooks

Info:

Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

191-194

Citation:

Online since:

June 2005

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2005 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] J.S. Chen, H. Lu, J. Richmond, D.L. Kaplan: Biomaterials Vol. 24 (2003), p.401.

Google Scholar

[2] H. Mori, M. Tsukada: Rev. Mol. Biotechno. Vol. 74 (2000), p.95.

Google Scholar

[3] L. Wang, R. Nemoto, M. Senna: J Eur Ceram Soc Vol. 24 (2004), p.2707.

Google Scholar

[4] L. Wang, R. Nemoto, M. Senna: J Mater Sci-Mater M Vol. 15 (2004), p.261.

Google Scholar

[5] R. Nemoto, S. Nakamura, T. Isobe, M. Senna: J. Sol-Gel Sci. Techn. Vol. 21 (2001), p.7.

Google Scholar

[6] B.M. Mina, G. Leea, S. H. Kimb, Y. S. Namb, T. S. Leeb, W. H. Parkb: Biomaterials Vol. 25 (2004), p.1289.

Google Scholar

[7] M. Santin, A. Motta, G. Freddi, M. Cannas: J Biomed Mater Res Vol. 46 (1999), p.382.

Google Scholar

[8] X.D. Kong, F.Z. Cui, X.M. Wang, M. Zhang, W. Zhang: J Cryst Growth (accepted).

Google Scholar

[9] S. S. Liao, F. Z. Cui, W. Zhang, Q. L. Feng: J. Biomed. Mater. Res. Part B Vol. 69B (2004) p.158.

Google Scholar

[10] M.C. Chang, C.C. Ko, W.H. Douglas: Biomaterials vol. 24 (2003), p.2853.

Google Scholar

[11] Z. Wei, Z.L. Huang, S.S. Liao, F.Z. Liao: J Am. Ceram Soc. Vol 86(6) (2003), p.1052.

Google Scholar