Synthesis and Biocompatibility Evaluation of Poly(HEMA-Co-MMA) Orbital Implant

Yi Ping Shi; Don Fang Yin; Ping Hu; Yi Fei Huang; Lin Liu

doi:10.4028/www.scientific.net/KEM.288-289.485

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Synthesis and Biocompatibility Evaluation of Poly(HEMA-Co-MMA) Orbital Implant
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 288-289Synthesis and Biocompatibility Evaluation of...

Synthesis and Biocompatibility Evaluation of Poly(HEMA-Co-MMA) Orbital Implant

Abstract:

Orbital implant, used for filling the space after enucleation, played an important role in the optical orthopedic operations. However, the clinical application of soft orbital implants was in a limited extent. This paper focused on the synthetic method of a new kind of soft poly (2-hydroxyethyl methacrylate) (PHEMA) orbital implant. This method included two steps, making the orbital implant with through-holes by salt leaking method and improving the compress property of PHEMA by copolymerizing it with methyl methacrylate (MMA). Scanning electronic microscope (SEM), thermo gravimetric analysis (TGA), and compress experiment were carried out to evaluate the physical properties of the implant. And to evaluate the biocompatibility of this poly (HEMA-co-MMA) orbital implant, short term and long term observations were studied after subcutaneous implantation of material blocks and implantation of orbital implants (diameter in 14mm) in rabbits’ orbits.

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Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

485-490

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.288-289.485

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Online since:

June 2005

Authors:

Yi Ping Shi, Don Fang Yin, Ping Hu, Yi Fei Huang, Lin Liu

Keywords:

Biocompatibility, Copolymerization, Evaluation, HEMA, MMA, Orbital Implant

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References

[1] N.J. Christmas, C.D. Gordon and T.G. Murray: A 10-year Review Arch Ophthalmology Vol. 166 (1998), pp.1199-203.

Google Scholar

[2] J.J. Dutton, et al: Ophthalmology Vol. 98 (1991), pp.370-77.

Google Scholar

[3] C.R. Hicks I.T. Morris and S. Vijayasekaran: British Journal of Ophthalmology (London 1999).

Google Scholar

[4] A.C. Perry: Ophthalmology North America Vol. 4 (1991), p.173.

Google Scholar

[5] H. Brettner, et al: America J Ophthalmology Vol. 113 (1992), p.669 Fig. 4 Picture after orbit implantation 12 weeks ×100 Fig. 5 HE coloration photo of implant slice ×100.

Google Scholar