Porous Ceramics of β-Tricalcium Phosphate Composed of Rod-Shaped Particles is Highly Biodegradable and Expresses Prominent Osteoconductivity

Takatoshi Okuda; Ikuho Yonezawa; Koji Ioku; Hideyuki Minagi; Hisashi Kurosawa; Tohru Ikeda

doi:10.4028/www.scientific.net/KEM.309-311.1063

Paper Titles

Effect of Cooling Rate and Particle Size on Compressive Strength of Macroporous Hydroxyapatite
p.1047

Surface Structure Design and Characterization of Bioabsorbable and Functionally Graded Apatites Originated from Bovine Bone
p.1051

Bimodal Porous β-TCP Ceramics and its Dissolution in Phosphate Buffer Saline
p.1055

Porous Granules of β-Tricalcium Phosphate Composed of Rod-Shaped Particles
p.1059

Porous Ceramics of β-Tricalcium Phosphate Composed of Rod-Shaped Particles is Highly Biodegradable and Expresses Prominent Osteoconductivity
p.1063

Preparation and Characterization of Porous Hydroxyapatite Block Using a HHP Method
p.1067

Preparation of Porous Hydroxyapatite / Tricalcium Phosphate Composite Block Using a HHP Method
p.1071

Preparation of Porous HA/Beta-TCP Biphasic Bioceramic Using a Molten Salt Process
p.1075

Preparation of Porous Composites with a Porous Framework Using Hydroxyapatite Whiskers and Poly(L-Lactic Acid) Short Fibers
p.1079

HomeKey Engineering MaterialsKey Engineering Materials Vols. 309-311Porous Ceramics of β-Tricalcium Phosphate Composed...

Porous Ceramics of β-Tricalcium Phosphate Composed of Rod-Shaped Particles is Highly Biodegradable and Expresses Prominent Osteoconductivity

Abstract:

Newly developed porous β-tricalcium phosphate composed of rod-shaped particles was grafted into distal end of the left femur of female Japan White rabbit. As a control, hydrixyapatite generated in the same size was grafted. In both implants, 350µm in diameter-sized holes were created vertically and horizontally. Three weeks after grafting, margin of the β-tricalcium phosphate was absorbed by osteoclasts and bone formation was seen near the absorbed region. Twenty-four weeks after grafting, more than 80% of the β-tricalcium phosphate was absorbed and newly formed bone was prominently observed. The hydroxyapatite was not remarkably absorbed even 24 weeks after grafting, and newly formed bone was observed only in the holes created in the implants. These results suggest that porous β-tricalcium phosphate composed of rod-shaped particles has highly biodegradable and osteoconductive nature, and appropriate to bone graft substitute.

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Periodical:

Key Engineering Materials (Volumes 309-311)

Pages:

1063-1066

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.309-311.1063

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Online since:

May 2006

Authors:

Takatoshi Okuda, Ikuho Yonezawa, Koji Ioku, Hideyuki Minagi, Hisashi Kurosawa, Tohru Ikeda

Keywords:

Bone Graft, Hydroxyapatite (HAP), β-Tricalcium Phosphate (β-TCP)

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