Preparation of Porous Composites with a Porous Framework Using Hydroxyapatite Whiskers and Poly(L-Lactic Acid) Short Fibers

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Abstract:

A new type of porous composite with a porous framework was prepared using a mixture of hydroxyapatite whiskers (W-HA) and poly(L-lactic acid) short fibers (F-PLLA) by a particle-leaching technique. The material, composed of a porous framework with interconnecting pore of >1 µm, has large-sized pores of about 200 µm. The large-sized pores were formed by leaching sucrose granules. The porosity can be controlled in the range from 60 to 85 % by the sucrose content. The small-sized pores in the framework formed due to the poor densification of the W-HAs / F-PLLAs mixture. The pore distribution in the framework can be controlled by the compressing pressure without change in the distribution of large-sized pores.

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Key Engineering Materials (Volumes 309-311)

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1079-1082

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May 2006

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© 2006 Trans Tech Publications Ltd. All Rights Reserved

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[1] L. E. Freed, J. C. Marquis, A. Nohria, J. Emmanual, A. G. Mikos, and R. Langer, J. Biomed. Mater. Res., Vol. 27 (1993) p.11.

DOI: 10.1002/jbm.820270104

Google Scholar

[2] F. Yang, R. Murugan, S. Ramakrishna, X. Wang, Y. X. Ma, and S. Wang, Biomaterials, Vol. 25 (2004) p.1891.

Google Scholar

[3] T. G. van Tienen, R. G. J. C. Heijkants, P. Buma, J. H. de Groot, A. J. Pennings and R. P. H. Veth, Biomaterials, Vol. 23 (2002) p.1731.

DOI: 10.1016/s0142-9612(01)00280-0

Google Scholar

[4] N. Tamai, A. Myoui, T. Kaito, T. Murase, T. Ueda, T. Ochi, and H. Yoshikawa, J. Joint Surgery , Vol. 23 (2004) p.100.

Google Scholar

[5] Y. Mizutani, M. Hattori, M. Okuyama, T. Kasuga and M. Nogami, J. Eur. Ceram. Soc., Vol. 25, (2005) p.3181.

Google Scholar

[6] Y. Mizutani, M. Hattori, M. Okuyama, T. Kasuga, and M. Nogami, Phosphorus Res. Bull., Vol. 17 (2004) p.180.

Google Scholar

[7] Y. Mizutani, M. Hattori, M. Okuyama, T. Kasuga, and M. Nogami, Polymer, Vol. 46 (2005) p.3789.

Google Scholar