Evaluation of Pore Architecture in Hydroxyapatite/Collagen Scaffold Using Micro Computed Tomography

Abstract:

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Hydroxyapatite/collagen (HAp/Col) composite scaffold with unidirectionally elongated pores (scaffold-U) was fabricated by the unidirectional solidification with ice growth and subsequent freeze-dry process. The pore architecture in the composite was evaluated by using scanning electron microscopy (SEM) and micro computed tomography (micro-CT) with a high resolution. The SEM observation showed that the scaffold-U had unidirectional pores elongated along the vertical direction (i.e. ice growth direction), however the horizontal cross-section showed quite different pore morphology: spindle-shaped pores with random direction. The 3-D micro-CT image of the scaffold-U simultaneously showed the microstructure of the unidirectionally elongated pore and the cross-sectional pore, indicating that the interconnected micropores were successfully fabricated along the ice growth direction. The micro-CT is a powerful tool for the visualization of 3-D pore structure.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

1091-1094

DOI:

10.4028/www.scientific.net/KEM.309-311.1091

Citation:

S. Yunoki et al., "Evaluation of Pore Architecture in Hydroxyapatite/Collagen Scaffold Using Micro Computed Tomography ", Key Engineering Materials, Vols. 309-311, pp. 1091-1094, 2006

Online since:

May 2006

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Price:

$35.00

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