Comparative Study of the Degradation Behavior of Mechanically Mixed and Chemically Precipitated Biphasic Calcium Phosphates
Surface morphology and degradation behavior of mechanically mixed and chemically precipitated biphasic calcium phosphate (M-BCP and P-BCP) were compared. For the M-BCP powder, commercial HA and TCP powders were used. In order to prepare P-BCP powder, precipitation method was used. The particle size of P-BCP was smaller than that of M-BCP. The disk-type specimens of each powder were prepared for the morphology comparison and degradation test. The surface morphology of sintered samples was porous in M-BCP and dense in P-BCP. The degradation test was conducted in the revised simulated body fluid (R-SBF) for 1, 7, and 21 days. Surface morphology and degradation rate of two samples were different. The weight gain in both samples increased linearly with immersion period due to apatite-like layer formation. However, the weight gain in M-BCP was much higher than that in P-BCP. The weight gain was related to the surface morphology and degradation with immersion period.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
D.J. Yang et al., "Comparative Study of the Degradation Behavior of Mechanically Mixed and Chemically Precipitated Biphasic Calcium Phosphates ", Key Engineering Materials, Vols. 309-311, pp. 227-230, 2006