Apatite-Forming Ability of Glass-Ceramics Containing Whitlockite and Diopside in a Simulated Body Fluid

Abstract:

Tricalcium phosphate (3CaO⋅P2O5, TCP) is known as a biodegradable material and already used clinically as important bone-repairing materials. However, the control of its bone-bonding ability, i.e. bioactivity, and biodegradability is not easy. On the other hand, diopside (CaO⋅MgO⋅2SiO2) ceramic shows a potential of direct contact with bone and high mechanical strength, but low biodegradability. We expected that a glass-ceramic containing TCP and diopside show high bioactivity and high mechanical strength, as well as biodegradability. Glasses with composition x(3CaO⋅P2O5)⋅(100-x) (CaO⋅MgO⋅2SiO2) (x = 0, 38, 50, 60 mass%) were prepared. They were pulverized and the compacts of the resultant powders were heated to obtain the glass-ceramics. Only diopside was precipitated at x = 0 in the glass composition, whitlockite (β-TCP) and diopside were at x = 38, 50 and 60, when the compacts were sintered at 1200 °C. The prepared glass-ceramics formed apatite on their surfaces in a simulated body fluid (SBF). This indicates that these glass-ceramics have a potential to show bioactivity.

• Periodical: Key Engineering Materials (Volumes 309-311)
• Pages: 341-344
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.309-311.341
• Online since: May 2006
• Authors: Masanobu Kamitakahara, Chikara Ohtsuki, Yuko Kozaka, Masao Tanihara, Toshiki Miyazaki
• Keywords: Apatite, Diopside, Glas Ceramics, Simulated Body Fluid (SBF)

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