TiO2-HDPE Composite: Bone Bonding Ability and Biocompatibility

Abstract:

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A novel material, namely, TiO2-HDPE (TiO2/high density polyethylene) composite was developed by our research group. Its mechanical properties are similar to those of the human cortical bone; hence, we examined the possibility of using it as a bone substitute. We prepared two groups of TiO2-HDPE; one was subjected to ultraviolet irradiation for 0.1 h and the other for 9 h. In bone bonding ability test, the former indicated a lower ability than the latter, which showed approximately 7 to 8 N of failure load. The bone bonding ability of the latter group alone is not sufficient for clinical application; on the other hand, the biocompatibility test was carried out. In the biocompatibility test, the group that was irradiated for 9 h revealed neither a major inflammatory response nor formation of neoplasm. We have to further examine alternate types of polyethylene or TiO2 particles in order to improve the bone bonding ability.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

415-418

DOI:

10.4028/www.scientific.net/KEM.309-311.415

Citation:

T. Nasu et al., "TiO2-HDPE Composite: Bone Bonding Ability and Biocompatibility ", Key Engineering Materials, Vols. 309-311, pp. 415-418, 2006

Online since:

May 2006

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Price:

$35.00

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