Effect of Bioactive Glass/Cement Weight Ratio on Bioactivity and Biocompatibility of a Bioactive Glass Modified Glass Ionomer Cement
The bioactivity of a glass ionomer luting cement (Ketac®-cem, ESPE, Germany), which was modified by Bioglass® (PerioGlas® Synthetic Bone Graft Particulate, US Biomaterials) in different bioglass/powder weight ratios, and the biocompatibility of the produced mixtures were evaluated in this study using different cell lines. The incorporation of Bioglass® in the cement structure resulted in the formation of sparsely located biological apatite aggregations. However, although Bioglass® incorporation seemed to enhance cell proliferation, the materials became eventually brittle and highly soluble depending on Bioglass® amount.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
E. Kontonasaki et al., "Effect of Bioactive Glass/Cement Weight Ratio on Bioactivity and Biocompatibility of a Bioactive Glass Modified Glass Ionomer Cement ", Key Engineering Materials, Vols. 309-311, pp. 877-880, 2006