In this study, mechanical degradations in 2.25Cr-1Mo steel were evaluated by quantitative morphological analysis of carbides. Based on the morphology, carbides were classified as globular, fine acicular, rod, and grain boundary one. Mean size of carbides were determined as a function of morphology and thermal degradation time at 630°C. Area fraction of grain boundary carbides and fraction of grain boundary M6C carbides were observed to increase rapidly in the initial stage of degradation and then gradually afterwards. Both mean size of globular carbide and fraction of grain boundary M6C carbides were linearly correlated with strength. Potentials of carbide morphology analysis as a health monitoring technique were discussed, in term of correlation coefficient with strength.