Synthesis of Poly(ε-Caprolactone)-Organosiloxane Hybrid Containing Amine Group

Abstract:

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Novel poly(ε-caprolactone)-organosiloxane hybrid containing amine group was synthesized through sol-gel method. Triethoxysilane end-capped poly(ε-caprolactone) was prepared by reaction with α,ω-hydroxyl poly(ε-caprolactone) and 3-isocyanatopropyl triethoxysilane. It was then hydrolyzed and co-condensed with aminopropyl triethoxysilane through sol-gel method. The success of hybridization was evaluated by FT-IR by new formation of siloxane group. Osteoblast-like cell responses were assessed on this new hybrid material for the potential application as a bone tissue engineering scaffold. The cell responses were compatible with those on pure poly(ε-caprolactone) used as a control.

Info:

Periodical:

Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu

Pages:

1277-1280

DOI:

10.4028/www.scientific.net/KEM.330-332.1277

Citation:

S. H. Rhee et al., "Synthesis of Poly(ε-Caprolactone)-Organosiloxane Hybrid Containing Amine Group", Key Engineering Materials, Vols. 330-332, pp. 1277-1280, 2007

Online since:

February 2007

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Price:

$35.00

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