Ultra-Thin Film of Chitosan and Sulfated Chitosan Coating on Titanium Oxide by Layer-by-Layer Self-Assembly Method
The ultra-thin film composed of chitosan (CS) and sulfated chitosan (SCS) was assembled on the titanium oxide surface by layer-by-layer (LBL) self-assembly methods. The titanium oxide film was treated by NaOH solution, followed by successively dipping the substrates in 5mg/ml sulfated chitosan (SCS) and 5mg/ml chitosan (CS) solutions alternatively, We hypothesized that this biologic coating may have the property of good biocompatibility, antibacteriostatic effect, anticoagulant activitves and enhancing sell biocompatibility.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Q. L. Li et al., "Ultra-Thin Film of Chitosan and Sulfated Chitosan Coating on Titanium Oxide by Layer-by-Layer Self-Assembly Method", Key Engineering Materials, Vols. 330-332, pp. 645-648, 2007