Improvement of Biocompatibility and Osteointegration of Zirconia Implants by Means of Bioactive Glass Coating: An Experimental Study in Animal

D.W. Yang; J.W. Zhu; W.G. Wu

doi:10.4028/www.scientific.net/KEM.336-338.1679

Paper Titles

Bone Formation in Non-Osseous Tissues of Biphasic HA/β-TCP Bioceramics Sintered by Different Ways
p.1666

Hydroxyapatite Coatings Deposited on Titanium Substrate by Pulsed Laser Deposition
p.1670

Preparation of Bioactive β-Tricalcium Phosphate Scaffold with Bone-Like Structure
p.1673

TEM Analysis on Bio-Functional Gradient Hydroxyapatite/ZrO₂ Coatings
p.1676

Improvement of Biocompatibility and Osteointegration of Zirconia Implants by Means of Bioactive Glass Coating: An Experimental Study in Animal
p.1679

Bioactive Ceramics - New Processing Technologies for Immobilization of Microorganisms for Filtration and Bioreactor Applications
p.1683

Preparation of Biphasic Calcium Phosphate Porous Ceramics Prepared from Fine Powders with Different Particle Size and its Dissolution Behavior in Simulated Body Fluid
p.1688

Apatite Forming on the Surface of Apatite-Wollastonite/β-Tricalcium Phosphate Bioactive Ceramic
p.1692

Simulation In Vitro of Subsonic Flame Sprayed Titanium/Biological Glass Composite Coating
p.1696

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Improvement of Biocompatibility and Osteointegration of Zirconia Implants by Means of Bioactive Glass Coating: An Experimental Study in Animal

Abstract:

The present work aimed to evaluate the biological properties between the bioglass coated and uncoated zirconia implants. A total of 24 implants were retrieved. Bioglass coated and uncoated porous implants were implanted in the mandible of 4 dogs. At the experimental times of 4 and 8 weeks after sacrifice, the histological sections specimens of the implants and surrounding tissues were processed to determine the osteointegration rate; The other corresponding implants were processed for SEM microanalysis. A significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in coated versus uncoated implants. The osteointegration rates varied between 21.5% and 47.7% (cancellous bone), and between 28.0% and 56.8% (cortical bone). (p < 0.05). SEM analysis demonstrated better bone adhesion to the material in coated implant at any weeks. Coated implants are highly biocompatible and osteoconductive.