Improvement of Biocompatibility and Osteointegration of Zirconia Implants by Means of Bioactive Glass Coating: An Experimental Study in Animal

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The present work aimed to evaluate the biological properties between the bioglass coated and uncoated zirconia implants. A total of 24 implants were retrieved. Bioglass coated and uncoated porous implants were implanted in the mandible of 4 dogs. At the experimental times of 4 and 8 weeks after sacrifice, the histological sections specimens of the implants and surrounding tissues were processed to determine the osteointegration rate; The other corresponding implants were processed for SEM microanalysis. A significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in coated versus uncoated implants. The osteointegration rates varied between 21.5% and 47.7% (cancellous bone), and between 28.0% and 56.8% (cortical bone). (p < 0.05). SEM analysis demonstrated better bone adhesion to the material in coated implant at any weeks. Coated implants are highly biocompatible and osteoconductive.

Info:

Periodical:

Key Engineering Materials (Volumes 336-338)

Edited by:

Wei Pan and Jianghong Gong

Pages:

1679-1682

DOI:

10.4028/www.scientific.net/KEM.336-338.1679

Citation:

D.W. Yang et al., "Improvement of Biocompatibility and Osteointegration of Zirconia Implants by Means of Bioactive Glass Coating: An Experimental Study in Animal", Key Engineering Materials, Vols. 336-338, pp. 1679-1682, 2007

Online since:

April 2007

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$38.00

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