Research on the Non-Contact Manipulation of Biomaterials in the Stationary Sound Field of Ultrasonic Transducers
For applying acoustic radiation force to manipulate biomaterials such as cell, DNA, bio-macromolecule without contact, stationary sound field of an ultrasonic transducer was computed numerically. With the numerical data about the sound field, spatial distribution of the acoustic radiation force was analyzed. Besides the radiation force in the axial direction, trapping forces in the lateral direction were discovered. By moving the reflector continuously and carefully, positions of trapping wells were changed simultaneously, as the result, non-contact manipulation of micro cells was implemented.
Yu Zhou, Shan-Tung Tu and Xishan Xie
Z. W. Fan et al., "Research on the Non-Contact Manipulation of Biomaterials in the Stationary Sound Field of Ultrasonic Transducers", Key Engineering Materials, Vols. 353-358, pp. 3035-3038, 2007