Calcium Phosphate Formation on Ethylphosphoester of Poly(ε-Caprolactone) and Poly[Bis(Methacrylate)]Phosphazene In Vitro

Abstract:

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Phosphorus containing biopolymers have been synthesized and studied as polymeric candidates for potential tissue engineering applications. The presence of phosphorus in the polymeric structure may improve the biocompatibility of polymers by enhancing their tissue contact. One aim of this study was to examine the chain extending reaction of poly(ε-caprolactone), PCL, using ethyldichlorophosphate as a coupling agent. A preliminary survey was done to find out whether the presence of phosphoester units in a rapidly degradable polymeric structure improves the Ca phosphate formation on PCL. Another aim of this study was to synthesize one kind of polyphosphazene, i.e. poly[bis(methacrylate)]phosphazene, PMAP. In addition, a preliminary biomineralization study for PMAP polymer was carried out. The results of the biomineralization studies indicated some bioactivity of both biopolymers.

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Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

171-174

DOI:

10.4028/www.scientific.net/KEM.396-398.171

Citation:

M. Puska et al., "Calcium Phosphate Formation on Ethylphosphoester of Poly(ε-Caprolactone) and Poly[Bis(Methacrylate)]Phosphazene In Vitro", Key Engineering Materials, Vols. 396-398, pp. 171-174, 2009

Online since:

October 2008

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$35.00

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