Visualization of Invasion into the Body and Internal Diffusion of Nanoparticles

Abstract:

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Nanoparticles may invade directly into the internal body through the respiratory or digestive system and diffuse inside body. The behavior of nanoparticles in the internal body is also essential to comprehend for the realization of DDS. Thus it is necessary to reveal the internal dynamics for the proper treatments and biomedical applications of nanoparticles. In the present study the plural methods with different principles such as X-ray scanning analytical microscope (XSAM), MRI and Fluorescent microscopy were applied to enable the observation of the internal diffusion of micro/nanoparticles in the (1) whole body level, (2) inner organ level and (3) tissue and intracellular level. Chemical analysis was also done by ICP-AES for organs and compared with the results of XSAM mapping.

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

569-572

DOI:

10.4028/www.scientific.net/KEM.396-398.569

Citation:

F. Watari et al., "Visualization of Invasion into the Body and Internal Diffusion of Nanoparticles ", Key Engineering Materials, Vols. 396-398, pp. 569-572, 2009

Online since:

October 2008

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Price:

$35.00

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