The Competition of the Retraction and Capillary Forces during the DNA Molecules Moving within Channels

Abstract:

The stretching processes of DNA molecules on the hydrophobic planar surfaces and the dynamic processes of DNA molecules moving into the micro- and nano-channels were studied with the fluorescence microscopy associated with the EMCCD in detail. The results demonstrated the ordered stretching of single DNA molecules under the effects of hydrophobic force, which is one of the main force should be considered when the DNA molecules are driven into channels or other nano-structure patterns.

• Periodical: Key Engineering Materials (Volume 483)
• Pages: 331-335
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.483.331
• Online since: June 2011
• Authors: Dan Hui, Kai Ge Wang, Xiao Juan Zhao, Qi Wei Qiao, Dan Li, Wei Jun Dang, Yun Wan, Jin Tao Bai
• Keywords: EMCCD, Micro-/Nano-Fluidic Channels, Retraction Force, Single DNA Molecule

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