Controlled Self-Coating of Implant Surfaces with Autologous Molecules

Martin Adam; Cornelia Ganz; W. Xu; B. Frerich; Thomas Gerber

doi:10.4028/www.scientific.net/KEM.529-530.207

Paper Titles

Evaluation of the Anti-Bacterial Activity of a Novel Chelate-Setting Apatite Cement Containing Lactoferrin
p.187

Basic Properties of Carbonate Apatite Cement Consisting of Vaterite and Dicalcium Phosphate Anhydrous
p.192

Preparation of Carbonate Apatite Cement Based on α-TCP
p.197

Improvement in Handling Property of αTCP Cement
p.202

Controlled Self-Coating of Implant Surfaces with Autologous Molecules
p.207

Hydroxyapatite and YSZ Reinforced Hydroxyapatite Coatings by Gas Tunnel Type Plasma Spraying
p.213

Laser-Assisted Biomimetic Process for Calcium Phosphate Coating on a Hydroxyapatite Ceramic
p.217

A Novel Approach to Prepare Hydroxyapatite-Coated Biodegradable Polymer Microspheres Loaded with Magnetic Fe₃O₄ via Nanoparticle-Stabilized Emulsions
p.223

Evaluation of Hydroxyapatite Film by Powder Jet Deposition after Artificial Aging
p.229

HomeKey Engineering MaterialsKey Engineering Materials Vols. 529-530Controlled Self-Coating of Implant Surfaces with...

Controlled Self-Coating of Implant Surfaces with Autologous Molecules

Abstract:

mplant fixation is correlated with direct bone apposition on the implant surface. In a former study it was reported that a new coating material enhances the bone-to-implant-contact in comparison to machined and rough surfaces. This study is aimed at clarifying the effect of an enhanced bone-to-implant-contact that is induced by a new coating material. The coating is produced by spin and spray coating and consists of a silica matrix, in which nanocrystalline hydroxyapatite is embedded. The coating material exhibits a high porosity in the micrometer and nanometer scale. Coated implants were inserted subcutaneously in Wistar Rats. The specimens were excised after 6 and 12 days. EDX and SEM analysis showed a reduction of the silica amount within 6 days. In accordance to former results of a bone grafting material with the same structure, this matrix change is responsible for an initial bone formation at early stages.

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Periodical:

Key Engineering Materials (Volumes 529-530)

Pages:

207-212

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.529-530.207

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Online since:

November 2012

Authors:

Martin Adam, Cornelia Ganz, W. Xu, B. Frerich, Thomas Gerber

Keywords:

Autologous, BIC, Coating, Hydroxyapatite (HAP), Implant, Matrix Change, Silica Matrix

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References

[1] L. LeGuehennec, A. Soueidan, P. Layrolle and Y. Amouriq, Surface treatments of titanium dental implants for rapid osseointegration. Dental Materials, 23: 844-854, (2007).

DOI: 10.1016/j.dental.2006.06.025

Google Scholar

[2] D. Buser, R.K. Schenk, S. Steinemann, J.P. Fiorellini, C.H. Fox and H. Stich, Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs, Journal of Biomedical Materials Research, 25: 889-902, (1991).

DOI: 10.1002/jbm.820250708

Google Scholar

[3] Liu, Y.; Enggist, L.; Kuffer, A. F.; Buser, D. & Hunziker, E. B. The influence of BMP-2 and its mode of delivery on the osteoconductivity of implant surfaces during the early phase of osseointegration, Biomaterials, 2007, 28, 2677-2686.

DOI: 10.1016/j.biomaterials.2007.02.003

Google Scholar

[4] M. Adam, C. Ganz, W. Xu, H.R. Sarajian, B. Frerich and Th. Gerber, How to enhance the Osseointegration – Roughness, Hydrophilicity or Bioactive Coating, KEM 493-494 (2012) 467-472.

DOI: 10.4028/www.scientific.net/kem.493-494.467

Google Scholar

[5] W. Götz, Th. Gerber, B. Michel, S. Lossdörfer, K. -O. Henkel, and F. Heinemann, Immunohistochemical characterization of nanocrystalline hydroxyapatite silica gel nanobone osteogenesis: a study on biopsies from human jaws, Clin. Oral Impl. Res., 19: 1016-1026, (2008).

DOI: 10.1111/j.1600-0501.2008.01569.x

Google Scholar

[6] W. Xu, G. Holzhüter, H. Sorg, D. Wolter, S. Lenz, Th. Gerber, B. Vollmar, Early Matrix Change of a Nanostructured Bone Grafting Substitute in the Rat, J Biomed Mater Res Part B: Appl Biomater 91B: 692–699, (2009).

DOI: 10.1002/jbm.b.31445

Google Scholar

[7] K. Donath and G. Breuner, A method for the study of undecalcified bones and teeth with attached soft tissues, Journal of Oral Pathology, 11: 318-326, (1982).

DOI: 10.1111/j.1600-0714.1982.tb00172.x

Google Scholar