A Novel Approach to Prepare Hydroxyapatite-Coated Biodegradable Polymer Microspheres Loaded with Magnetic Fe₃O₄ via Nanoparticle-Stabilized Emulsions

Abstract:

HAp-nanoparticle-coated biodegradable polymer microspheres loaded with magnetic Fe₃O₄ particles can be successfully prepared by evaporating volatile oil (dichloromethane) from HAp-nanoparticle-stabilized oil droplets containing biodegradable polymer and Fe₃O₄ particles without any molecular surfactants or polymeric stabilizers. In this study it was found that the hydrophobic surface modification for the Fe₃O₄ particles was a key factor to prepare stable HAp-nanoparticle-stabilized oil droplets (and HAp-nanoparticle-coated polymer microspheres) loaded with magnetic Fe₃O₄ particles.

• Periodical: Key Engineering Materials (Volumes 529-530)
• Pages: 223-228
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.529-530.223
• Online since: November 2012
• Authors: Masahiro Okada, Shoji Takeda, Tsutomu Furuzono
• Keywords: Biodegradable Polymer, Coating, Emulsion, Hydroxyapatite (HAP), Magnetic, Nanoparticle

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