Study of the C60 Fullerene on Differentiation of Mouse Embryonic Stem Cells

Abstract:

The risks of nanomaterials for future generations should be elucidated. Thus, it is important to establish an experimental method to accurately examine embryotoxicity. We have conducted an in vitro embryotoxicity test with mouse ES cells to examine the embryotoxicities of various nanomaterials. In this study, the C60 fullerene did not influence the differentiation of ES-D3 cells and "non embryotoxicity". In the future, the biological safety should be comprehensively examined by improving dispersion in medium.

• Periodical: Key Engineering Materials (Volumes 529-530)
• Pages: 385-390
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.529-530.385
• Online since: November 2012
• Authors: Koichi Imai, Fumio Watari, Kazuaki Nakamura, Akito Tanoue
• Keywords: C60 Fullerene, Embryotoxicity, Es Cells, EST

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