Comparative Critical Study of Commercial Calcium Phosphate Bone Substitutes in Terms of Physic-Chemical Properties

Abstract:

Physico-chemical characteristics impact directly or indirectly the bioactive properties of biomaterials, it is then essential to correlate it with their effect in vivo. A panel of biomaterials available on the market, based on Hydroxyapatite (HA) and Tricalcium phosphate (β-TCP) is studied in terms of surface area, hydrophilicity, porosity, zeta potential, crystalline phases and density. This study highlights the dispersity of commercial calcium phosphates (CaP) properties, and demonstrates how the quality criteria required for such bone substitute based on biomimicry concept, whose pores distribution is certainly the more relevant, are often incompletely or not respected according to literature.

• Periodical: Key Engineering Materials (Volume 587)
• Pages: 63-68
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.587.63
• Online since: November 2013
• Authors: T. Miramond, Pascal Borget, Serge Baroth, Daculsi Guy
• Keywords: Bone Substitute, Calcium Phosphate, Microstructure, Pore Distribution, Specific Surface Area

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