Preparation and Development of Bioglass by Sol-Gel Method

Abstract:

Bioglass is a good bioactive material and has been used in many medical fields, include drug delivery systems, non-load-bearing implants and bone cements. Sol-gel is a good method in the preparation of coating materials. It also can be used in the preparation of bioactive glass. In this paper, the principles and technical processes are introduced. The effects on characteristics of bioactive glasses of the factors such as H₂O dosage, ethanol dosage, gel temperature and activator are analyzed in detail. The research progress in preparation of sol-gel bioactive glasses is summarized. Finally the development foreground of sol-gel bioglass is also expected.

• Periodical: Key Engineering Materials (Volume 591)
• Pages: 34-39
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.591.34
• Online since: November 2013
• Authors: Chuan Zhong Chen, Xiang Guo Meng, Hui Jun Yu, Han Yang, Ting He, Dian Gang Wang, Shi Gui Zhao
• Keywords: Bioactivity, Bioglass, Influencing Factor, Preparation, Research Progress, Sol-Gel

References

[1] G. Gollera, H. Demirkirana, F.N. Oktarb, E. Demirkesen, Processing and Characterization of Bioglass Reinforced Hydroxyapatite Composites, Ceram. Int. 29 (2003) 721-724.

DOI: 10.1016/s0272-8842(02)00223-7

[2] J.L. Liu, X.G. Miao, Sol–gel derived bioglass as a coating material for porous alumina scaffolds Ceram. Int. 30 (2004) 1781-1785.

DOI: 10.1016/j.ceramint.2003.12.120

[3] I. Notingher, A.R. Boccaccini, J. Jones, V. Maquet, L.L. Hench, Application of Raman microspectroscopy to the characterisation of bioactive materials, Mater. Charact. 49 (2003) 255-260.

DOI: 10.1016/s1044-5803(03)00029-9

[4] L.L. Hench, Sol-gel materials for bioceramic applications, Curr. Opin. Solid St. M. 2 (1997) 604-610.

[5] E.E. Stroganova, N.Y. Mikhailenko, O.A. Moroz, Glass-based biomaterials: present and future (a review), Glass Ceram. 60 (2003) 315-319.

DOI: 10.1023/b:glac.0000008235.49161.32

[6] D.M. Liu, T. Troczynski, W.J. Tseng, Aging effect on the phase evolution of water-based sol-gel hydroxyapatite, Biomaterials. 23 (2002) 1227-1236.

DOI: 10.1016/s0142-9612(01)00242-3

[7] C.M. Lopatin, V. Pizziconi, T.L. Alford, T. Laursen, Hydroxyapatite powders and thin films prepared by a sol-gel technique, Thin Solid Films. 36 (1998) 227-232.

DOI: 10.1016/s0040-6090(98)00531-8

[8] M.M. Pereira, A.E. Clark, L.L. Hench, Homogeneity of bioactive sol-gel derived glasses in the system CaO-P2O5-SiO2, J. Mater. Synth. Proces. 2(3) (1994) 189-196.

[9] J.D. Mackenzie, Sol-Gel Research—Achievements since 1981 and Prospects for the Future J. Sol-Gel Sci. Techn. 26 (2003) 23-27.

[10] G. Bezzi, G. Celotti, E. Landi, T.M. G La Torretta, I. Sopyan, A. Tampieri, A novel sol–gel technique for hydroxyapatite preparation, Mater. Chem. Phys. 78 (2003) 816-824.

DOI: 10.1016/s0254-0584(02)00392-9

[11] M.M. Pereira, A.E. Clark, L.L. Hench, Calcium phosphate formation on sol-gel derived bioactive glasses in vitro, J. Biomed. Mater. Res. 28(6) (1994) 693-698.

DOI: 10.1002/jbm.820280606

[12] J. Xu, Eoin S. O'Keefe, Carole C. Perry, The preparation and characterization of sol-gel zinc silicate glass particles with pyramid shape and millimetre size, J. Mater. Chem. 14 (2004) 1744-1748.

DOI: 10.1039/b314524g

[13] N.N. Ghosh, Synthesis of nanostructured mullite and mullite-zirconia ceramic composite powders by using a modified and cost effective sol-gel method, CESP. 24(3) (2003) 99-104.

DOI: 10.1002/9780470294802.ch15

[14] X.H. Hong, B.G. Li, Principle and Application of Sol-Gel Method, J. Tianjin Normal Univ. -Nat. Sci. Edit. 21 (2001) 5-8.

[15] Z.D. Chen, H. Zou, Applications of sol-gel method in preparation of biomaterials, J. Biomed. Eng. 18 (2001) 629-638.

[16] Y.R. Cai, L. Zhou, K.G. Wang, Z.T. Yu, J.L. Niu, Preparation of bioglass ultrafine powder by sol-gel-self-propagating process, J Mater. Sci. Eng. 22(5) (2004) 637-639.

[17] G.S. Xu, D.P. Wang, W.L. Huang, The production of A/W glass-ceramic by sol-gel method, J. Tongji Univ. -Med. Sci. 26(2) (2005) 12-16.

[18] N. Li, Q. Jie, S.M. Zhu, R.D. Wang, A new route to prepare macroporous bioactive sol–gel glasses with high mechanical strength, Mater. Lett. 58 (2004) 2747-2750.

DOI: 10.1016/j.matlet.2004.03.049

[19] W.Y. Zhao, J. Chang, Sol-gel synthesis and in vitro bioactivity of tricalcium silicate powders, Mater. Lett. Vol. 58 (2004) 2350-2353.

DOI: 10.1016/j.matlet.2004.02.045

[20] A. Oki, B. Parveen, S. Hossain, S. Adeniji, H. Donahue, Preparation and in vitro bioactivity of zinc containing sol-gel-derived bioglass materials, J. Biomed. Mater. Res. A. 69(2) (2004) 216-221.

DOI: 10.1002/jbm.a.20070

[21] J.P. Zhong, D.C. Greenspan, Processing and properties of sol-gel bioactive glasses, J. Biomed. Mater. Res. 53(6) (2000) 694-701.

DOI: 10.1002/1097-4636(2000)53:6<694::aid-jbm12>3.0.co;2-6