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Treatment of Chronic Bone Infections Using the Collagen Based Haemostatic - Collatamp G

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Abstract:

Treating chronic bone infection is challenging, requiring complete excision of the affected areas and antimicrobial therapy. Acquiring active concentrations of antibiotics is difficult, as well as filling up bone defects resulting from sequestrectomy, and very few methods of treatment address both issues simultaneously. The authors describe the clinical results after using Collatamp G, a collagen-based, antibiotic filled sponge with two actions: local delivery of high antibiotic doses without systemic side effects and enhancement of healing due to collagen, thus covering the bone defect without any further osteoplastic surgery. This paper thus identifies Collatamp G as a biomaterial able to solve the above mentioned problems in treating bone infections.Keywords: bone infections, collagen matrix, gentamicine, antibiotic delivery

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Periodical:

Key Engineering Materials (Volume 695)

Pages:

133-138

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.695.133

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Online since:

May 2016

Authors:

Olivera Lupescu*, Mihail Nagea, Cristina Patru, Alexandru Dimitriu, Nicolae Ciurea, Doriana Lupescu, Gheorghe Ion Popescu, Narcis Marcov

Keywords:

Antibiotic Delivery, Bone Infections, Collagen Matrix, Gentamicine

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© 2016 Trans Tech Publications Ltd. All Rights Reserved

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