One-Pot Synthesis of Chloropyridines from Aminopyridines via Diazotization

Yulia Lesina; Perizat Beysembay; Assiya Kassanova

doi:10.4028/www.scientific.net/KEM.712.273

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HomeKey Engineering MaterialsKey Engineering Materials Vol. 712One-Pot Synthesis of Chloropyridines from...

One-Pot Synthesis of Chloropyridines from Aminopyridines via Diazotization

Abstract:

A method for synthesis of chloropyridines from pyridinyl trifluoromethanesulfonates in acetonitrile in the presence of hydrochloric acid was developed. One-pot synthesis of chloropyridines from aminopyridines via diazotization was presented. Pyridyl triflates were obtained in this reaction in situ. This method provides good yields of the target products.

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Key Engineering Materials (Volume 712)

Pages:

273-276

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.712.273

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Online since:

September 2016

Authors:

Yulia Lesina*, Perizat Beysembay, Assiya Kassanova

Keywords:

Aminopyridines, Chloropyridines, Diazotization, Pyridinyl Trifluoromethanesulfonates, Trifluomethanesulfonic Acid

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