Vapour Diffusion Route to Mineralize Graphene and Polymer Surfaces with Calcium Phosphate Intended for Biomedical Applications

Abstract:

After successful application of the sitting drop vapour diffusion route to deposit calcium phosphate layers on mica muscovite sheets, in this work we have extended the method to mineralize polymer surfaces (OSTE+) and bidimensional materials (graphene), aimed to prepare implants or scaffolds for nonload bearing applications in the medical sector. Thin octacalcium phosphate/apatite layers have been deposited on mica muscovite sheets. Thin apatite/octacalcium phosphate layers deposited on OSTE+ polymer lames. When graphene nanoflakes where used as support, this technique yielded apatite/graphene nanocomposites.

• Periodical: Key Engineering Materials (Volume 758)
• Pages: 210-214
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.758.210
• Online since: November 2017
• Authors: Jaime Gómez-Morales*, Luis Antonio González-Ramírez, Cristóbal Verdugo-Escamilla, Isaac Rodríguez-Ruiz, Giuseppe Falini
• Keywords: Calcium Phosphate, Coatings, Graphene, Mica, OSTE+, Vapour Diffusion Route

References

[1] K. de Groot, J.G.C. Wolke, J.A. Jansen, Calcium phosphate coatings for medical implants, Proc. Inst. Mech. Eng. H–J. Eng. Med. 212 (1998) 137–147.

DOI: 10.1243/0954411981533917

[2] J. Gómez-Morales, R. Rodríguez-Clemente, B. Armas, C. Combescure, R. Berjoan, J. Cubo, E. Martinez, J. Garcia-Carmona, S. Garelik, J. Murtra, D. N. Muraviev, Controlled nucleation and growth of thin hydroxyaopatite layers on Titanium implants by using induction heating technique, Langmuir, 20 (2004).

DOI: 10.1021/la0363682

[3] R. A. Surmenev, M. A. Surmeneva, A. A. Ivanova, Significance of calcium phosphate coatings for the enhancements of new bone osteogenesis-A review, Acta Biomater. 10, 2 (2014) 557-579.

DOI: 10.1016/j.actbio.2013.10.036

[4] M. Iafisco, J. Gómez-Morales, M.A. Hernández-Hernández, M. García Ruiz, N Roveri, Biomimetic carbonate-hydroxyapatite nanocrystals prepared by vapour diffusion, Adv. Engn. Mater. 12, 7 (2010) B218-B223.

DOI: 10.1002/adem.201080003

[5] J. Gómez-Morales, C. Verdugo-Escamilla, J.A. Gavira-Gallardo, Bioinspired calcium phosphate coated mica sheets by vapor diffusion and its effects on lysozyme assembly and crystallization, Cryst. Growth & Des. 16 (2016) 5150-5158.

DOI: 10.1021/acs.cgd.6b00716

[6] A. Ciesielski A, P. Samori. Graphene via sonication assisted liquid-phase exfoliation, Chem. Soc. Rev. 43 (2014) 381-398.

DOI: 10.1039/c3cs60217f

[7] J.M. Delgado-López, M. Iafisco, I. Rodríguez, A. Tampieri, M. Prat, J. Gómez-Morales, Crystallization of bioinspired citrate-functionalized nanoapatite with tailored carbonate content, Acta Biomater. 8, 9 (2012) 3491-3499.

DOI: 10.1016/j.actbio.2012.04.046

[8] C.E. Hoyle, C.N. Bowman, Thiol–ene click chemistry, Angew. Chem. Int. Ed, 49 (2010) 1540-1573.

[9] E. J. Tsang, C. K. Arakawa, P. A. Zuk, B. M. Wu, Osteoblast interactions within a biomimetic apatite microenvironment, Ann. Biomed. Eng., 39, 4 (2011) 1186-1200.

DOI: 10.1007/s10439-010-0245-6

[10] Y. Hao, Y. Wang, L. Wang, Z. Ni, Z. Wang, R. Wang, C.K. Koo, Z. Shen, J.T.L. Thong, Probing layer number and stacking order of few-layer graphene by Raman spectroscopy, Small 6, 2 (2010) 195-200.

DOI: 10.1002/smll.200901173

[11] G. B. Ramírez-Rodríguez, J.M. Delgado-López, J. Gómez-Morales, Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situ Raman microspectroscopy , CrystEngComm 15 (2013) 2206-2212.

DOI: 10.1039/c2ce26556g