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HomeKey Engineering MaterialsKey Engineering Materials Vol. 840Highly Efficient Synthesis of Oxindole Derivatives...

Highly Efficient Synthesis of Oxindole Derivatives Via Catalytic Intramolecular C-H Insertion Reactions of Diazoamides

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Abstract:

Oxindole derivatives were efficiently synthesized from diazoamides derived from aniline derivatives in the presence of a Ru(II)-Pheox catalyst. Ru(II)-Pheox was found to be one of the most efficient catalysts so far for the synthesis of oxindole derivatives from the diazoamides in high yields (up to 99%) with high regioselectivity. Furthermore, the reaction was rapid and no substituent effects on the aromatic ring.

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Symposium of Materials Science and Chemistry II

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Periodical:

Key Engineering Materials (Volume 840)

Pages:

251-256

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.840.251

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Online since:

April 2020

Authors:

Phan Thi Thanh Nga, Masaya Tone, Hayato Inoue, Kazutaka Shibatomi, Seiji Iwasa*

Keywords:

Carbene, C-H Insertion Reaction, Oxindole, Ruthenium, α-Diazoamide

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© 2020 Trans Tech Publications Ltd. All Rights Reserved

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