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HomeKey Engineering MaterialsKey Engineering Materials Vol. 840The Porosity and Human Gingival Cells Attachment...

The Porosity and Human Gingival Cells Attachment of Synthetic Coral Scaffold for Bone Regeneration

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Abstract:

Porosity and interconnectivity play an important role in the success of tissue engineering because it affects cells to live and grow. Coral has been used as a bone replacement material because the structures resemble bone and have mechanical bone properties. In this study, the synthetic coral scaffold was developed to mimic the natural coral. This study aims to investigate the porosity of the scaffold and its biocompatibility while it is attached to human gingival cells. Synthetic coral scaffold in various compositions were prepared, porosity percentage measurement and human gingival cell attachment test were done. An optimum ratio of the scaffold with gelatin: CaCO₃, having the highest porosity and cell attachment is obtained in 5:5. The result of this study presented that synthetic coral scaffold could provide the microenvironment to cells for life because it is supported by the highest percentage of porosity.

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Symposium of Materials Science and Chemistry II

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Key Engineering Materials (Volume 840)

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305-310

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https://doi.org/10.4028/www.scientific.net/KEM.840.305

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Online since:

April 2020

Authors:

Erlina Sih Mahanani*, Indra Bachtiar, Ika Dewi Ana

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Attachment, Human Gingival Cells, Porosity, Synthetic Coral Scaffold

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© 2020 Trans Tech Publications Ltd. All Rights Reserved

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