Application of the CO₂ Laser Photoacoustic Spectroscopy in Detecting Ammonia Gas (NH₃) in Liver Disease Patient’s Breath

Abstract:

Using a CO₂ laser photoacoustic spectroscopy with intracavity setup and multicomponent method we have done measurement on the ammonia, ehtylene and acetone gas concentrations in the breath of liver disease patients and in the healthy volunteers. The results of multicomponent analysis show that the average concentration of ammonia gas obtained from the breath of liver disease patients and healthy volunteers are (3.27 ± 0.75) and (1.34 ± 0.24) ppm, respectively. The highest and the lowest ammonia gas concentration of liver disease patients are 4.77 and 1.99 ppm. While, the highest and the lowest ammonia gas concentration of healthy volunteers are 1.89 and 1.08 ppm. For the ethylene and acetone concentrations, we found no significant difference between the average concentrations in the liver disease patients and in the healthy volunteers.

• Periodical: Key Engineering Materials (Volume 840)
• Pages: 399-405
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.840.399
• Online since: April 2020
• Authors: Mitrayana Mitrayana*, Muhamad Azhar Maarif, Mohammad Ali Joko Wasono, Mohammad Robikhul Ikhsan, Mirza Satriawan
• Keywords: Ammonia, CO₂ Laser Photoacoustic Spectroscopy, Liver

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