Silicon Nitride Surface Modification and Cell Adhesion

Yi Zhao; Xiao Ying Lv; Zheng Lin Jiang; Xia Li; Yan Huang; Zhigong Wang

doi:10.4028/www.scientific.net/MSF.610-613.1022

Paper Titles

Development of Surface Treatment in Industrial Scale for Components with Metallic Luster on AZ31 Sheets
p.999

Effect of SF₆ Cover Gas Humidity and Concentration on Efficient Protection of Molten Magnesium
p.1003

In Vitro Cytotoxicity Study of the Nano-Hydroxyapatite/Bacterial Cellulose Nanocomposites
p.1011

Functionality of Ti-O Thin Films Doped by Phosphorus: Wettability, Semiconductor Performance and Blood Compatibility
p.1017

Silicon Nitride Surface Modification and Cell Adhesion
p.1022

Improvement of Tribological Behaviour of Biomedical Nanocrystalline Titanium by Magnetron Sputtered DLC/SiC Double Layer Films
p.1026

Fabrication of Novel Cellulose/Chitosan Artificial Skin Composite
p.1034

POSS/TiO₂ Nanohybrids as Sun Protection Factors for Skin Changes Caused by Ultraviolet A Radiation
p.1039

Preparation and Properties of Calcium Phosphate Cement Containing ZnO Whisker
p.1044

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Silicon Nitride Surface Modification and Cell Adhesion

Abstract:

Silicon microelectrode arrays (Si MEAs) have great potential in recording of neural activity; the biocompatibility of silicon nitride has gained much attention as a part of Si MEAs. In this study, we used alternating polycations, polyethyleneimine (PEI), and polyanions, gelatin, to fabricate multilayer films built up by LbL deposition on silicon nitride wafers. Then the samples surfaces were characterized by contact angle system and atomic force microscopy (AFM). The amount of proteins adsorbed on silicon nitride and modified silicon nitride were measured by a modified Coomassie brilliant blue (CBB) protein assay. Cell culture results showed that the modified silicon nitride could increase the adhesion ability of the hippocampal neurons.