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Fabrication of Artificial Bone by the Combination of Electrospinning, Extrusion and Slurry Processes
Abstract:
In this work, we focused on the manufacture of artificial bone for medical replacement based on the combination of individual properties of ceramic and polymer. Here, periosteum was fabricated with a HAp (Hydroxylapatite) frame, while compact bone was fabricated from multi-layer electro-spun PS (polystyrene)/PCL (polycaprolactone) using biocompatible collagen glue. Spongy bone is formed from PCL/PLGA spongy loading BCP (Biphasic Calcium Phosphate) powder coated collagen. SEM images showed successful fabrication of the artificial bone scaffold through a combination of electro-spinning, extrusion, and use of the slurry method.
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2233-2236
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Online since:
June 2010
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© 2010 Trans Tech Publications Ltd. All Rights Reserved
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