Synthesis and Characterization of Ionic Crosslinked Chitosan Scaffolds

Thiago Bezerra Fideles; Ana C.B.M. Fook; Gloria T.F.S. Furtado; Italo M.F. Pinheiro; Marcus Vinícius Lia Fook

doi:10.4028/www.scientific.net/MSF.805.26

Paper Titles

Nitinol Alloys - Study of Physical and Chemical Application as Biomaterials
p.3

Development of MTA/HAp Biomaterials for Use in Endodontics
p.7

Glass Ionomer Cement – Development and Characterization Microstructural
p.12

Biocompatibility of Dental Restorative Materials
p.19

Synthesis and Characterization of Ionic Crosslinked Chitosan Scaffolds
p.26

Evaluation of the Cytotoxic Potential Chitosan/Hydroxyapatite Biocomposites
p.30

Sterilization of Chitosan Membranes for Use as Biomaterial
p.35

Evaluation of the Terms of Use of Recycled Polymer Packaging Co-Extruded
p.41

Study of Non-Conformities of Hip Prosthesis Metal Front Standards
p.47

HomeMaterials Science ForumMaterials Science Forum Vol. 805Synthesis and Characterization of Ionic...

Synthesis and Characterization of Ionic Crosslinked Chitosan Scaffolds

Abstract:

Chitosan has been the focus of an extensive research in recent years, especially due to its biodegradability, biocompatibility and the possibility to be processed in many form, shapes and sizes. Besides, chitosan can ben chemically modified and this modification through crosslinking can produce materials with a wide variety of properties. The aim of this present work was to produce and characterizing ionic crosslinked chitosan scaffolds. Chitosan scaffolds were prepared by the freeze drying technique and crosslinking was introduced by a chemical reaction with sulfuric acid solution. The non-crosslinked and crosslinked chitosan scaffolds were characterized by Fourier Transformed Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Energy Dispersive Spectroscopy (EDS). According to FTIR results, an effective reaction between the sulfate ions and chitosan scaffolds was achieved with visible changes in the spectra. This reaction also could be seen on EDS results with sulfur peaks presents in all the crosslinked samples. The SEM results showed that the crosslinking reaction doesn ́t modified the chitosan scaffolds tridimensional structure.

You might also be interested in these eBooks

A Special Issue in Memory of Dr. Lucio Salgado

View Preview

Info:

Periodical:

Materials Science Forum (Volume 805)

Pages:

26-29

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.805.26

Citation:

Cite this paper

Online since:

September 2014

Authors:

Thiago Bezerra Fideles*, Ana C.B.M. Fook, Gloria T.F.S. Furtado, Italo M.F. Pinheiro, Marcus Vinícius Lia Fook

Keywords:

Characterization, Chitosan, Crosslink, Scaffold

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] B Dhandayuthapanin, Y. Yoshida, T. Maekawa and D.S. Kumar: International Journal of Polymer Science (2011), p.01.

Google Scholar

[2] W.W. Thein-Han and R.D. K Misra: Acta Biomaterialia Vol. 5 (2009), p.1182.

Google Scholar

[3] T. Uragami and S. Tokura: Materials Science of Chitin and Chitosan. (Kodansha Ltd. Japan, 2006).

Google Scholar

[4] J. Berger, M. Reist, J.M. Mayer, O. Felt, N.A. Peppas and R. Gurny: European Journal of Pharmaceutics and Biopharmaceutics Vol. 57 (2004), p.19.

DOI: 10.1016/s0939-6411(03)00161-9

Google Scholar

[5] T.B. Fidéles, In: Filmes Reticulados de Quitosana para Aplicação como Biomaterial. 2010. 92p. Dissertação (Mestrado em Ciência e Engenharia de Materiais) – Universidade Federal de Campina Grande. Campina Grande, (2010).

DOI: 10.14393/19834071.2015.30311

Google Scholar