Solvatochromism and Electroabsorption Studies of Drug Carriers

Abstract:

2, 6-Diaminoanthraquinone is used in drug delivery. The absorption and fluorescence spectral properties of 2,6-Diaminoanthraquinone (DAAQ) have been investigated in a series of organic solvents with different polarity functions ranging from 0.207 to 0.762.The different solvents used are Tetrahydrofuran (THF) (0.207), Dimethylformamide (DMF) (0.404), ethanol (0.654) and Methonal (0.762).The fluorescence shifts are more pronounced than the absorption shifts indicating that the change in dipole moment is positive. The change in dipole moment and the ratio of the dipole moments are determined and discussed by Solvatochromism method. The third order nonlinearity of 2,6-DAAQ in PVA dissolved in DMF solution is determined using Electroabsorption. Higher order nonlinearities can be deduced on successful recording of the stark spectrum at the higher order of the applied electric field.

• Periodical: Materials Science Forum (Volume 807)
• Pages: 169-176
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.807.169
• Online since: November 2014
• Authors: R. Jothilakshmi*, R. Rajeswari, E. Thanikaivelan
• Keywords: 2,6-diaminoanthraquinone, Electroabsorption, Solvatochromism, Third Order Nonlinearity

References

[1] C. Reichardt, Solvatochromic Dyes as Solvent Polarity Indicators, Chem. Rev. 94, (1994), 2319.

DOI: 10.1021/cr00032a005

[2] V. Sasirekha, V. Ramakrishnan, Study of preferential solvation of 2, 6-diaminoanthra-quinone in binary mixtures by absorption and fluorescence studies, Spectrochim Acta., 70, (2007), 626.

DOI: 10.1016/j.saa.2007.08.013

[3] S. R. Flom, P. F. Barbara, Proton transfer and hydrogen bonding in the internal conversion of S1 anthraquinones, J. Phys. Chem. 89, (1985), 4489.

DOI: 10.1021/j100267a017

[4] Kawski, Z. Naturforsch, On the Estimation of Excited-State Dipole Moments from Solvatochromic Shifts of Absorption and Fluorescence, SpectraActa Phys. Polon,. 57a, (2002), 255.

DOI: 10.1515/zna-2002-0509

[5] V. A. Gunyakov, A. M. Parshin and V. F. Shabanov, Temperature dependence of the effective anchoring energy for a nematic-ferroelectric interface, Eur. phys. J. E 20, (2006), 467.

DOI: 10.1140/epje/i2006-10037-9

[6] W. D. R. Joseph, N. R. Pradhan, Suneel Singh and D. Narayan Rao, Electroabsorption spectroscopy: A versatile tool to measure optical nonlinearities Current Science, 86, (2004), 1283.

[7] Kawski, B. Kuklinski, P. Bojarski and Z. Naturforsch. Thermochromic Absorption, Fluorescence Band Shifts and Dipole Moments of BADAN and ACRYLODAN, 57a, (2002), 716-722.

DOI: 10.1515/zna-2002-0812

[8] G. B. Dutt, M. K. Singh and A.V. Sapre, Rotational dynamics of neutral red: Do ionic and neutral solutes experience the same friction, J. Chem. Phys., 109, (1998), 8498.

DOI: 10.1063/1.477225

[9] H. Kim, J. S. Horwitz, A. Pique and C.M. Gilmore, Study of AZO Thin Films Under Different Ar Flow and Sputtering Power by rf Magnetron Sputtering, App. Phys. A, 86, (1998), 5447-5450.

[10] R. B. Hadj Jahar, T. Ban, Y. Ohya, and Y. Takahashi, Tin doped indium oxide thin films: Electrical properties, J. App. Phys., 83, (1998), 2631.

DOI: 10.1063/1.367025

[11] H. Kim and C. M. Gilmore, Electrical, optical, and structural properties of indium–tin–oxide thin films for organic light-emitting devices, J. App. Phys., 86, (1999), 6451.

DOI: 10.1063/1.371708

[12] T. Vijayalakshmi, Solvatochromism and Electroabsorption studies on Rhodamine B dye M. Phil Dissertation, School of physics, University of Hyderabad, (2005).

[13] A. Fathima, M. Umadevi, V. Ramakrishnan, 4-N, N-dimethylaminobenzonitrile: the absence of a∗ fluorescence under jet-cooled conditions, J. Fluoresc , 18, (2008), 383.