Observed Phenomena during the Development of an Adhesion Test for Coated Medical Devices

Abstract:

Devices used in the field of medical technology require high biocompatibility. Medical devices that are made from stainless steel have good biocompatible properties, but polymer coatings can radically improve it. One of the most important quality of the coating is adhesion, and this was our rationale for developing a polymer adhesion testing protocol. In our research, two biocompatible polymers were compared, polyurethane (PUR) and poly-(DL-lactic-co-glycolic acid) (PDLG). Surface-treated stainless steel sheets were used as carrier for polymer layers. The adhesive properties of different layers were compared. Adhesion of the coatings was characterised by concentration of coating solution and surface roughness of the carriers, and some phenomena were observed.

• Periodical: Materials Science Forum (Volume 812)
• Pages: 381-386
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.812.381
• Online since: February 2015
• Authors: Torda László Sélley*, Anna Kertész, Eszter Bognár
• Keywords: Adhesion, Biocompatible Metal, Biocompatible Polymer, Coating, PLGA, PUR, Stainless Steel

References

[1] H.F. Hildebrand, N. Blanchemain et al, Surface coatings for biological activation and functionalization of medical devices, Surface and Coatings Technology. EMRS 2005 Symposium K — Protective Coatings and Thin Films: 2005 May 31 – June 3: Strasbourg(FR) (2006).

DOI: 10.1016/j.surfcoat.2005.11.086

[2] G. Mani, M. D. Feldman, et al, Coronary stents: A materials perspective, Biomaterials 28 (2007) 1689-1710.

DOI: 10.1016/j.biomaterials.2006.11.042

[3] H. W. Fang, K. Y. Li, et al, Dip coating assisted polylactic acid deposition on steel surface: Film thickness affected by drag force and gravity, Material Letters (2008) 62 (21-22) 3739-3741.

DOI: 10.1016/j.matlet.2008.04.046

[4] H. Ollendorf, D. Schneider, A comparative study of adhesion test methods for hard coatings, Surface and Coatings Technology (1999) 113 (1-2) 86-102.

DOI: 10.1016/s0257-8972(98)00827-5

[5] M. El-Shabasí, Perspective of adhesion of thin films, Electrical Engineering and Computer Science, (1981) 25-2 123-134.

[6] E. V. Cortés, M. A. Lorenzo, et al, Adhesion Testing of Epoxy Coating, Texas Department of Transportation, 1998 Sept.

[7] C. S. Litteken, R. H. Dauskardt, Adhesion of polymer thin-films and patterned lines, International Journal of Fracture (2003) 119/120 475-485.

DOI: 10.1023/a:1024940132299

[8] T. L. Sélley, A. Terdik, E. Bognár, Biológiailag lebomló polimerbevonatok tapadásának vizsgálata (Investigation of biodegradable polymer coatings' adhesion test), Fiatal Műszakiak Tudományos Ülésszaka XVIII 2013 March 21–22 Kolozsvár (RO).

DOI: 10.36243/fmtu-2013.78

[9] T. Newson, Stainless Steel – A Family of Medical Device Materials, Business Briefing: Medical Device Manufacturing & Technology (2002) London (UK).

[10] R. W. Smith, New Developments and Trends in Medical-grade Adhesives, Medical Device Manufacturing & Technology (2004) London (UK).

[11] Y. Onuki, U. Bhardwaj, M. P. F. Papadimitrakopoulos, D. J. Burgess, A Review of the Biocompatibility of Implantable Devices: Current Challenges to Overcome Foreign Body Response, J Diabetes Sci Technol. (2008) November 2 (6) 1003–1015.

DOI: 10.1177/193229680800200610

[12] J. M. Anderson, M. S. Shive, Biodegradation and biocompatibility of PLA and PLGA microspheres, Advanced Drug Delivery Reviews (1997) 28 5–24.

DOI: 10.1016/s0169-409x(97)00048-3

[13] A. Raval, A. Choubey, H. Kotadia, et al, Novel Biodegradable Polymeric Matrix Coated Cardiovascular Stent For Controlled Drug Delivery, Trends Biomater. Artif. Organs (2007) 2 101-110.

[14] D. Fejős, P. Sütő, K. Molnár, B. Pukánszky, PU/PBT keverékek vizsgálata esetleges orvosi alkalmazásra, (Examination of PU / PBT blends for possible medical applications), Műanyag és Gumi (2011) 48 (12) 446-449.