Silver Doped Nano-Sized Bioglass Ceramics: Synthesis, Characterization and Biocompatibility Studies

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We report on the structural and biocompatibility properties of nanosized calcium phosphosilicate bioglass ceramics doped with 0, 2, 4 and 6 mol% Ag2O. Silver doped bioceramics were synthesized by sol-gel method. The prepared samples were characterized by means of powder X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, UV-visible and high resolution transmission electron microscopy. The XRD reveals the glass-ceramic nature of the samples. The FT-IR spectra show the possible stretching and bending vibrations of silicate and phosphate groups. Absorptions in UV-visible spectra reveal the silver embedment as Ag+/Ago form into the glass matrix. nanosize of the glass ceramics is confirmed by HR-TEM analysis. The bioactivity of silver doped bioceramics was investigated by in-vitro method with Dulbecco’s Modified Eagel’s Medium. It confirms the formation of bone-like hydroxylapatite layer formation on the surface of bioceramics.

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25-28

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July 2016

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© 2016 Trans Tech Publications Ltd. All Rights Reserved

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